de Oliveira Deane Cristina da Rocha Rodrigues, da Paz Wandklebson Silva, Bezerra-Santos Márcio, Dos Santos Priscila Lima, Tavares Débora Dos Santos
Program in Applied Health Sciences, Federal University of Sergipe, Lagarto, Sergipe, Brazil.
Program in Tropical Medicine, Federal University of Pernambuco, Recife, Pernambuco, Brazil.
Trop Med Int Health. 2025 Sep;30(9):908-920. doi: 10.1111/tmi.14141. Epub 2025 Jun 22.
To evaluate the temporal trend and spatial distribution of oral cancer cases in Brazil, and to evaluate the relationship between oral cancer cases and socioeconomic conditions.
Data on oral cancer cases, between 2013 and 2019, were extracted from the Painel-Oncologia website, and the socioeconomic indicators selected were Municipal Human Development Index and Social Vulnerability Index. The endpoints were late diagnosis (staging III and IV) and delay in treatment (>60 days), along with oral cancer prevalence. Spearman's correlation was done between oral cancer cases and Municipal Human Development Index/ Social Vulnerability Index. Temporal trends were evaluated using a segmented linear regression model. As for spatial analysis, global and local Moran indices were applied, together with spatiotemporal scan statistics, to detect risk clusters.
In the period studied, there was a prevalence of 5.3 oral cancer cases/100,000 inhabitants. A significant inverse correlation was found with the Social Vulnerability Index, and a direct correlation linking the Municipal Human Development Index and oral cancer cases, delayed treatment, and diagnosis cases too. An increasing trend of oral cancer prevalence rate and a stable trend of delayed diagnosis and treatment cases were observed in the country. There was a concentration of oral cancer cases in the South and Southeast regions. A high-risk oral cancer cluster was identified covering the South and Southeast regions, and part of the Midwest region and four secondary clusters of delayed treatment cases in the Northeast region.
There was no short-term improvement in data related to oral cancer in Brazil, since the prevalence trend was increasing and there was a correlation with socioeconomic conditions.
评估巴西口腔癌病例的时间趋势和空间分布，并评估口腔癌病例与社会经济状况之间的关系。
从Painel-Oncologia网站提取2013年至2019年期间的口腔癌病例数据，所选的社会经济指标为市人类发展指数和社会脆弱性指数。终点指标为晚期诊断（III期和IV期）和治疗延迟（>60天），以及口腔癌患病率。对口腔癌病例与市人类发展指数/社会脆弱性指数进行Spearman相关性分析。使用分段线性回归模型评估时间趋势。至于空间分析，应用全局和局部莫兰指数以及时空扫描统计来检测风险聚集区。
在研究期间，口腔癌病例的患病率为5.3/10万居民。发现与社会脆弱性指数呈显著负相关，市人类发展指数与口腔癌病例、延迟治疗和诊断病例之间也呈正相关。该国观察到口腔癌患病率呈上升趋势，延迟诊断和治疗病例呈稳定趋势。口腔癌病例集中在南部和东南部地区。确定了一个覆盖南部和东南部地区以及中西部地区部分地区的口腔癌高风险聚集区，以及东北地区的四个延迟治疗病例的二级聚集区。
巴西与口腔癌相关的数据短期内没有改善，因为患病率呈上升趋势且与社会经济状况相关。
