雌二醇和孕酮对去卵巢小鼠纹状体多巴胺和酪胺浓度的影响。
The effects of estradiol and progesterone on the concentration of striatal dopamine and tyramine in ovariectomized mice.
作者信息
Yeung S C, Juorio A V
出版信息
Gen Pharmacol. 1985;16(5):517-9. doi: 10.1016/0306-3623(85)90015-1.
PMID:4054576
Abstract
The concentration of homovanillic acid and p-tyramine in the female corpus striatum were increased after ovariectomy. The increases were reversed by chronic administration of estradiol benzoate and potentiated by progesterone. It is proposed that these changes are the consequence of concomitant variations in p-tyrosine availability.
摘要
去卵巢后，雌性大鼠纹状体中高香草酸和对酪胺的浓度升高。长期给予苯甲酸雌二醇可逆转这种升高，而孕酮则会增强这种升高。有人提出，这些变化是对酪氨酸可利用性同时变化的结果。
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