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引用本文的文献

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本文引用的文献

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THE ESTIMATION OF SMALL QUANTITIES OF 3,4-DIHYDROXYPHENYLETHYLAMINE IN TISSUES.组织中少量3,4-二羟基苯乙胺的测定
Br J Pharmacol Chemother. 1965 Apr;24(2):538-48. doi: 10.1111/j.1476-5381.1965.tb01744.x.
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BLOCKADE OF ENDOGENOUS NOREPINEPHRINE SYNTHESIS BY ALPHA-METHYL-TYROSINE, AN INHIBITOR OF TYROSINE HYDROXYLASE.酪氨酸羟化酶抑制剂α-甲基酪氨酸对内源性去甲肾上腺素合成的阻断作用
J Pharmacol Exp Ther. 1965 Jan;147:86-95.
3
On the occurrence of homovanillic acid in brain and cerebrospinal fluid and its determination by a fluorometric method.关于高香草酸在脑和脑脊液中的存在及其荧光法测定
Life Sci (1962). 1963 Jul(7):448-58. doi: 10.1016/0024-3205(63)90132-2.
4
The effect of mesencephalic lesions on tyramine and dopamine in the caudate nucleus of the rat.中脑损伤对大鼠尾状核中酪胺和多巴胺的影响。
J Neurochem. 1981 Jun;36(6):1898-903. doi: 10.1111/j.1471-4159.1981.tb10813.x.
5
Interactions between p-tyramine, m-tyramine, or beta-phenylethylamine and dopamine on single neurones in the cortex and caudate nucleus of the rat.对大鼠大脑皮层和尾状核单个神经元中对-酪胺、间-酪胺或β-苯乙胺与多巴胺之间相互作用的研究。
Can J Physiol Pharmacol. 1980 Feb;58(2):222-7. doi: 10.1139/y80-038.
6
Conversion of L-tyrosine to 3,4-dihydroxyphenylalanine by cell-free preparations of brain and sympathetically innervated tissues.通过脑和交感神经支配组织的无细胞制剂将L-酪氨酸转化为3,4-二羟基苯丙氨酸。
Biochem Biophys Res Commun. 1964;14:543-9. doi: 10.1016/0006-291x(64)90266-9.
7
Changes in dopamine levels in the corpus striatum following lesions in the substantia nigra.黑质损伤后纹状体内多巴胺水平的变化。
Exp Neurol. 1969 Mar;23(3):332-40. doi: 10.1016/0014-4886(69)90081-8.
8
Enhancement of tyrosine hydroxylation within the brain by chlorpromazine.氯丙嗪对脑内酪氨酸羟化作用的增强。
Experientia. 1969 Sep 15;25(9):919-20. doi: 10.1007/BF01898062.
9
Identification and distribution of p-tyramine in the rat.大鼠体内对酪胺的鉴定与分布
Can J Biochem. 1974 May;52(5):366-73. doi: 10.1139/o74-055.
10
Dopaminergic neurons: similar biochemical and histochemical effects of gamma-hydroxybutyrate and acute lesions of the nigro-neostriatal pathway.多巴胺能神经元：γ-羟基丁酸与黑质-新纹状体通路急性损伤的相似生化和组织化学效应。
J Pharmacol Exp Ther. 1973 Sep;186(3):630-9.

γ-羟基丁酸对小鼠纹状体酪胺、多巴胺和高香草酸的影响。

The effect of gamma-hydroxybutyrate on mouse striatal tyramine, dopamine and homovanillic acid.

作者信息

Juorio A V

出版信息

Br J Pharmacol. 1982 Mar;75(3):447-50. doi: 10.1111/j.1476-5381.1982.tb09160.x.

DOI:10.1111/j.1476-5381.1982.tb09160.x
PMID:7066598
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2071564/
Abstract

1 The concentrations of p- and m-tyramine, dopamine and homovanillic acid were measured in the mouse striatum following the subcutaneous injection of gamma-hydroxybutyrate; their control levels were 19.8, 6.3, 9600 and 1130 ng/g respectively. 2 The administration of 500-1000 mg/kg of gamma-hydroxybutyrate produced a reduction in p-tyramine that lasted at least 8 h. m-Tyramine and dopamine were significantly increased for at least 4 h. The levels of homovanillic acid were increased at 1 and 2 h after drug administration. 3 There experiments strongly suggest that the increases in dopamine turnover produced by gamma-hydroxybutyrate caused reciprocal changes in striatal tyramine that are similar to those produced by drug or treatment that increase dopamine turnover and tyrosine hydroxylase activity.

摘要
  1. 在皮下注射γ-羟基丁酸后，测定了小鼠纹状体中对-酪胺、间-酪胺、多巴胺和高香草酸的浓度；它们的对照水平分别为19.8、6.3、9600和1130 ng/g。2. 给予500 - 1000 mg/kg的γ-羟基丁酸会使对-酪胺减少，且至少持续8小时。间-酪胺和多巴胺显著增加至少4小时。给药后1小时和2小时高香草酸水平升高。3. 这些实验有力地表明，γ-羟基丁酸引起的多巴胺周转率增加导致纹状体酪胺发生相反变化，这与增加多巴胺周转率和酪氨酸羟化酶活性的药物或治疗所产生的变化相似。