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一家区综合医院的计算机断层结肠成像(CTC)应用:一项回顾性分析。

Utilization of Computed Tomography Colonography (CTC) at a District General Hospital: A Retrospective Analysis.

作者信息

Javaid Ali, Anwar Kehkashan, Zeb Ehtisham, Large Harry, Qureshi Nafees

机构信息

General and Colorectal Surgery, Tameside and Glossop Integrated Care NHS Foundation Trust, Manchester, GBR.

General Surgery, Tameside and Glossop Integrated Care NHS Foundation Trust, Manchester, GBR.

出版信息

Cureus. 2025 May 20;17(5):e84490. doi: 10.7759/cureus.84490. eCollection 2025 May.

Abstract

Colorectal cancer (CRC) is one of the most common cancers worldwide, necessitating efficient diagnostic pathways. While colonoscopy remains the gold standard, computed tomography colonography (CTC) offers a non-invasive alternative, particularly for elderly and comorbid patients. This retrospective study, conducted at a UK district general hospital (DGH), evaluated patterns of CTC utilization among patients referred for colonic investigations over a 12-month period. Despite CTC's high diagnostic accuracy (93% sensitivity for polyps > 10 mm) and its suitability for high-risk populations, it was used as a first-line investigation in only 3.5% of cases, markedly lower than the 12%-15% reported in tertiary centers. Contributing factors included limited radiologist training, restricted CT scanner capacity, and a prevailing institutional preference for colonoscopy. Addressing these DGH-specific barriers, such as resource constraints and workforce limitations, is critical to enhancing CTC's role within the two-week-wait (2WW) pathway. This study underscores the need for multicenter research to validate these findings and guide policy development, ensuring equitable access to non-invasive diagnostics for frail, comorbid, or preference-driven populations.

摘要

结直肠癌(CRC)是全球最常见的癌症之一,因此需要有效的诊断途径。虽然结肠镜检查仍是金标准,但计算机断层扫描结肠成像(CTC)提供了一种非侵入性替代方法,尤其适用于老年患者和患有合并症的患者。这项在英国一家地区综合医院(DGH)进行的回顾性研究,评估了在12个月期间转诊进行结肠检查的患者中CTC的使用模式。尽管CTC具有较高的诊断准确性(对直径>10mm的息肉敏感性为93%)且适用于高危人群,但它仅在3.5%的病例中被用作一线检查,明显低于三级中心报告的12%-15%。促成因素包括放射科医生培训有限、CT扫描仪容量受限以及机构普遍倾向于结肠镜检查。解决这些特定于DGH的障碍,如资源限制和劳动力限制,对于增强CTC在两周等待(2WW)途径中的作用至关重要。这项研究强调需要进行多中心研究以验证这些发现并指导政策制定,确保为体弱、患有合并症或有特定偏好的人群公平提供非侵入性诊断方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbf5/12179423/26c6c0233666/cureus-0017-00000084490-i01.jpg

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