Wongrostrai Yupha, Chiangkhong Araya, Suwanwong Charin, Khunakorncharatphong Anon
Kuakarun Faculty of Nursing, Navamindradhiraj university, Bangkok, Thailand.
Behavioral Science Research Institute, Srinakharinwirot University, Bangkok, Thailand.
F1000Res. 2025 Jun 5;13:1445. doi: 10.12688/f1000research.154968.2. eCollection 2024.
Stroke survivors, particularly those of working age, are at an increased risk of recurrent stroke within one-five years of the initial event, largely due to suboptimal management of risk factors. This study aimed to identify lifestyle and occupational factors associated with recurrent stroke in this demographic population.
This case-control study included 100 patients with recurrent ischemic stroke and 200 ischemic stroke survivors without recurrence, who were recruited from the hospital database. Multivariate logistic regression was used to identify significant factors associated with recurrence, which were presented as adjusted odds ratios (aORs) with 95% confidence intervals (CIs).
The mean age was 45.4 years (SD = 15.1) among cases and 50.6 years (SD = 6.5) among controls. The male-to-female ratios were 1.17:1 and 1.94:1 in the case and control groups, respectively. Significant factors associated with recurrent stroke included female sex (aOR: 1.83; 95% CI [1.10-3.29]), high fasting blood sugar (aOR: 3.70; 95% CI [1.66-8.27]), current alcohol consumption (aOR: 3.63; 95% CI [2.01-6.54]), sedentary lifestyle (aOR: 2.77; 95% CI [1.50-5.13]), and lack of workplace support for health (aOR: 2.02; 95% CI [1.13-3.63]). The associations between these factors and stroke recurrence varied according to the age group.
This study highlights the critical role of modifiable lifestyle and occupational factors in stroke recurrence among working-age adults. Tailored age-specific prevention strategies-emphasizing physical activity, reduced alcohol use, and improved workplace health environments-may reduce the risk of recurrence and enhance health outcomes in this population.
中风幸存者，尤其是处于工作年龄的幸存者，在首次中风事件后的一至五年内复发中风的风险增加，这主要是由于危险因素管理欠佳所致。本研究旨在确定该人群中与复发性中风相关的生活方式和职业因素。
这项病例对照研究纳入了100例复发性缺血性中风患者和200例未复发的缺血性中风幸存者，他们均从医院数据库中招募。采用多因素逻辑回归分析来确定与复发相关的显著因素，以调整后的比值比（aOR）及其95%置信区间（CI）表示。
病例组的平均年龄为45.4岁（标准差=15.1），对照组为50.6岁（标准差=6.5）。病例组和对照组的男女比例分别为1.17:1和1.94:1。与复发性中风相关的显著因素包括女性（aOR：1.83；95%CI[1.10 - 3.29]）、空腹血糖高（aOR：3.70；95%CI[1.66 - 8.27]）、当前饮酒（aOR：3.63；95%CI[2.01 - 6.54]）、久坐不动的生活方式（aOR：2.77；95%CI[1.50 - 5.13]）以及工作场所缺乏健康支持（aOR：2.02；95%CI[1.13 - 3.63]）。这些因素与中风复发之间的关联因年龄组而异。
本研究强调了可改变的生活方式和职业因素在工作年龄成年人中风复发中的关键作用。针对特定年龄的预防策略——强调体育活动、减少饮酒以及改善工作场所的健康环境——可能会降低该人群的复发风险并改善健康结局。
