Two case reports of rare cocaine-associated dermatoses: Pyoderma gangrenosum and linear IgA bullous dermatosis.

We report two cases of cocaine-associated dermatoses: pyoderma gangrenosum and linear IgA bullous dermatosis. These cases highlight the importance of considering less common associations with drug use in the development of certain dermatoses. Eliciting a good history around the onset of the skin condition and potential triggers is vital in establishing a causal link. In both of our cases, the lesions improved with cocaine avoidance and disease-specific treatment. Use of cocaine is most commonly associated with vasculitis, but has been reported to trigger neutrophilic dermatoses and vesiculobullous diseases. Dermatologists need to be aware of these less common cocaine-associated dermatoses, particularly when patients are not responding to standard therapy alone.