Shang Yu, Jiang Yinhua, Chen Yuanming, Fu Haibiao, Li Fengdan
School of Medicine, Lishui University. Lishui 323000, China. E-mail:
Shanghai Kou Qiang Yi Xue. 2025 Apr;34(2):202-207.
To investigate the effect of nonsurgical periodontal therapy on blood glucose control in patients with type 2 diabetes mellitus (T2DM) and chronic periodontitis, as well as the sensitive population.
A total of 120 patients with T2DM and chronic periodontitis who were admitted to the Department of Endocrinology at Lishui City People's Hospital from March 2022 to March 2023 were randomly divided into experimental group and control group, with 60 patients in each group. All patients received oral health education, and their general information, community periodontal index (CPI), attachment loss (AL), fasting plasma glucose (FPG), and haemoglobin A1c (HbA1c) were collected. The experimental group received periodontal scaling and root planing. Three months later, CPI, AL, FPG, and HbA1c were measured. Stata 15.0 software was used for statistical analysis.
After periodontal scaling and root planing, the CPI, FPG, and HbA1c in the experimental group were significantly lower than those before treatment(P＜0.01) and those in the control group(P＜0.05). AL in the experimental group was also significantly lower than before treatment(P＜0.05) and the control group (P＜0.05). The change of FPG after treatment was positively correlated with the duration of diabetes (P＜0.01) and the baseline CPI(P＜0.05), but negatively correlated with whether suffering from hypertension(P＜0.05). It was also negatively correlated with the FPG level before treatment (P＜0.01). The change of HbA1c after treatment was positively correlated with the duration of diabetes(P＜0.05) and negatively correlated with the HbA1c level before treatment(P＜0.01).
Nonsurgical periodontal therapy is helpful to blood sugar control of type 2 diabetes patients with periodontitis. Patients with higher baseline CPI levels and longer disease durations show greater improvement in glycemic control after treatment.
探讨非手术牙周治疗对2型糖尿病（T2DM）合并慢性牙周炎患者血糖控制的影响以及敏感人群。
选取2022年3月至2023年3月在丽水市人民医院内分泌科住院的120例T2DM合并慢性牙周炎患者，随机分为实验组和对照组，每组60例。所有患者均接受口腔健康教育，并收集其一般资料、社区牙周指数（CPI）、附着丧失（AL）、空腹血糖（FPG）和糖化血红蛋白（HbA1c）。实验组接受牙周洁治和根面平整术。3个月后，测量CPI、AL、FPG和HbA1c。采用Stata 15.0软件进行统计分析。
牙周洁治和根面平整术后，实验组的CPI、FPG和HbA1c均显著低于治疗前（P＜0.01）及对照组（P＜0.05）。实验组的AL也显著低于治疗前（P＜0.05）及对照组（P＜0.05）。治疗后FPG的变化与糖尿病病程（P＜0.01）和基线CPI（P＜0.05）呈正相关，但与是否患有高血压（P＜0.05）呈负相关。它还与治疗前的FPG水平呈负相关（P＜0.01）。治疗后HbA1c的变化与糖尿病病程（P＜0.05）呈正相关，与治疗前的HbA1c水平呈负相关（P＜0.01）。
非手术牙周治疗有助于2型糖尿病合并牙周炎患者的血糖控制。基线CPI水平较高和病程较长的患者在治疗后血糖控制改善更大。
