Li Xinlou, Wang Ganghui, Wang Haoxiang, Wang Aijia, Guo Hongxu
College of Chemistry, Chemical Engineering and Environment, Minnan Normal University, Zhangzhou, 363000, China.
Fujian Province Key Laboratory of Modern Analytical Science and Separation Technology, Minnan Normal University, Zhangzhou, 363000, China.
Mikrochim Acta. 2025 Jun 23;192(7):447. doi: 10.1007/s00604-025-07304-9.
AgCl/Ag@MOF(Ag) nanocomposites have been successfully fabricated through a simple and quick one-pot reflux approach for the first time, where AgCl/Ag nanoclusters are stabilized on the sheet-like MOF(Ag) surface. The as-prepared Ag-based MOFs fluorescent probe shows high fluorescence intensity and excellent fluorescence stability for sensing of tetracycline antibiotics (TCs) through mechanisms involving inner filter effect (IFE) and static quenching. The experimental results show that the detection concentration ranges for tetracycline (TET), chlortetracycline (CTC), and oxytetracycline (OTC) were 10-80 μM, 10-60 μM, and 10-30 μM, and with the detection limits of 2.59 nM, 1.36 nM, and 1.43 nM, respectively. The high sensitivity and selectivity of the fluorescent probe for TCs offers novel perspectives on utilizing supported MOFs as fluorescent probes for trace TCs detection in food by a fast, simple, and reliable method.
首次通过一种简单快速的一锅回流法成功制备了AgCl/Ag@MOF(Ag)纳米复合材料，其中AgCl/Ag纳米团簇稳定在片状MOF(Ag)表面。所制备的基于Ag的MOF荧光探针通过内滤光效应（IFE）和静态猝灭机制对四环素类抗生素（TCs）传感表现出高荧光强度和优异的荧光稳定性。实验结果表明，四环素（TET）、金霉素（CTC）和土霉素（OTC）的检测浓度范围分别为10 - 80 μM、10 - 60 μM和10 - 30 μM，检测限分别为2.59 nM、1.36 nM和1.43 nM。该荧光探针对TCs的高灵敏度和选择性为利用负载型MOF作为荧光探针通过快速、简单且可靠的方法检测食品中的痕量TCs提供了新的视角。
