关于生物制剂在儿童哮喘中应用的真实世界证据：已有相关证据但仍不完善？

Real-world evidence on biologic use in paediatric asthma: there but not there yet?

作者信息

Chen Wenjia

机构信息

Saw Swee Hock School of Public Health, National University of Singapore, Singapore.

出版信息

ERJ Open Res. 2025 Jun 23;11(3). doi: 10.1183/23120541.00209-2025. eCollection 2025 May.

DOI:10.1183/23120541.00209-2025

PMID:40551792

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12183747/

Abstract

https://bit.ly/4deHEpq.

摘要

https://bit.ly/4deHEpq. （此为网址，无法准确翻译为中文，保留原文）

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本文引用的文献

[1]

Inflammatory and clinical risk factors for asthma attacks (ORACLE2): a patient-level meta-analysis of control groups of 22 randomised trials.

Lancet Respir Med. 2025-6

[2]

Comparative effectiveness of dupilumab and omalizumab on asthma exacerbations and systemic corticosteroid prescriptions: Real-world US ADVANTAGE study.

J Allergy Clin Immunol. 2024-12

[3]

Factors influencing the initiation of biologic therapy in children with severe asthma: Results of the pediatric asthma noninvasive diagnostic approaches (PANDA) study.

Pediatr Pulmonol. 2024-11

[4]

Reduction of daily maintenance inhaled corticosteroids in patients with severe eosinophilic asthma treated with benralizumab (SHAMAL): a randomised, multicentre, open-label, phase 4 study.

Lancet. 2024-1-20

[5]

Unanswered questions on the use of biologics in pediatric asthma.

World Allergy Organ J. 2023-11-3

[6]

Impact of Initiating Biologics in Patients With Severe Asthma on Long-Term Oral Corticosteroids or Frequent Rescue Steroids (GLITTER): Data From the International Severe Asthma Registry.

J Allergy Clin Immunol Pract. 2023-9

[7]

Evaluating the Value for Money of Precision Medicine from Early Cycle to Market Access: A Comprehensive Review of Approaches and Challenges.

Value Health. 2023-9

[8]

Can we predict who will benefit most from biologics in severe asthma? A post-hoc analysis of two phase 3 trials.

Respir Res. 2023-5-2

[9]

Biologic Therapies in Pediatric Asthma.

J Pers Med. 2022-6-18

[10]

Reducing Tolerance for SABA and OCS towards the Extreme Ends of Asthma Severity.

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关于生物制剂在儿童哮喘中应用的真实世界证据：已有相关证据但仍不完善？

Real-world evidence on biologic use in paediatric asthma: there but not there yet?

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机构信息

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