Cohen Adi, Gunthner Andrew, Cervone Adam, Uzwy Madison, Urban-Galvez Stephanie N
Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, USA.
Pediatrics, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, USA.
Cureus. 2025 May 24;17(5):e84741. doi: 10.7759/cureus.84741. eCollection 2025 May.
Obstructive sleep apnea (OSA) is an under-recognized consequence of pediatric obesity, with adenotonsillectomy (AT) serving as the standard first-line surgical treatment. In obese pediatric patients, OSA often recurs postoperatively, raising concern for the long-term efficacy of AT. This systematic review evaluates the recurrence of OSA in post-AT obese pediatric patients, with a focus on the key risk factors contributing to residual disease. A literature search was conducted using Embase, PubMed, and Web of Science. Eligibility criteria included peer-reviewed, English articles published within the last five years that contained pediatric patients less than 18 years old who had a body mass index (BMI) ≥ 95th percentile. All patients had to have been diagnosed with sleep-disordered breathing or OSA preoperatively and must have undergone AT. Eleven studies met these criteria, of which 82% demonstrated a significant association between obesity and recurrence of OSA following AT. Key factors included higher baseline apnea-hypopnea index, postoperative weight gain, and residual upper airway obstruction. Two studies contradicted this trend, but limitations such as the use of subjective questionnaires and short follow-up durations reduced the studies' reliability. The findings indicate that AT alone is often insufficient in resolving OSA in obese pediatric patients. Given the high recurrence rates, a multidisciplinary approach, including weight management and non-invasive ventilation, may be needed to improve outcomes in this vulnerable population.
阻塞性睡眠呼吸暂停(OSA)是小儿肥胖症一个未得到充分认识的后果,腺样体扁桃体切除术(AT)是标准的一线外科治疗方法。在肥胖小儿患者中,OSA术后常复发,这引发了对AT长期疗效的担忧。本系统评价评估了AT术后肥胖小儿患者中OSA的复发情况,重点关注导致残留疾病的关键危险因素。使用Embase、PubMed和Web of Science进行了文献检索。纳入标准包括过去五年内发表的经同行评审的英文文章,这些文章包含年龄小于18岁、体重指数(BMI)≥第95百分位数的小儿患者。所有患者术前均须被诊断为睡眠呼吸障碍或OSA,且必须接受过AT。11项研究符合这些标准,其中82%表明肥胖与AT术后OSA复发之间存在显著关联。关键因素包括较高的基线呼吸暂停低通气指数、术后体重增加和残留上气道阻塞。两项研究与这一趋势相悖,但诸如使用主观问卷和随访时间短等局限性降低了研究的可靠性。研究结果表明,单纯AT往往不足以解决肥胖小儿患者的OSA问题。鉴于高复发率,可能需要一种多学科方法,包括体重管理和无创通气,以改善这一脆弱人群的治疗效果。