Ohta Yumi, Ozono Yoshiyuki, Suzuki Motoyuki, Sato Takashi, Inohara Hidenori
Department of Otorhinolaryngology-Head and Neck Surgery, National Hospital Organization Osaka Medical Center, Osaka, JPN.
Department of Otorhinolaryngology-Head and Neck Surgery, The University of Osaka Faculty of Medicine, Suita, JPN.
Cureus. 2025 May 24;17(5):e84755. doi: 10.7759/cureus.84755. eCollection 2025 May.
The case is of a 60-year-old woman with a history of radiotherapy for parotid adenoid cystic carcinoma. Twenty years after irradiation, a papilloma developed in the left external auditory canal. Nine years after excision of the papilloma, a squamous cell carcinoma developed in the same region. This is a rare case of squamous cell carcinoma following treatment for a papilloma and is considered radiation-induced cancer. Because re-irradiation is not possible as a treatment for radiation-induced cancer, it is necessary to diagnose the cancer early so that curative resection is possible. Multiple biopsies should be considered when malignancy is suspected because a single biopsy may not be sufficient to diagnose an auditory canal tumor.
该病例为一名60岁女性，有腮腺腺样囊性癌放疗史。放疗20年后，左侧外耳道出现乳头状瘤。乳头状瘤切除9年后，同一区域发生鳞状细胞癌。这是一例乳头状瘤治疗后发生鳞状细胞癌的罕见病例，被认为是放射性癌症。由于放射性癌症无法再次放疗，因此有必要早期诊断癌症以便进行根治性切除。当怀疑为恶性肿瘤时，应考虑进行多次活检，因为单次活检可能不足以诊断耳道肿瘤。
