Rahul Neha, Jules Manishimwe, Weerarathna Induni Nayodhara, Luharia Anurag, Dube Prashik
Department of Radio Oncology, Datta Meghe Institute of Higher Education and Research (Deemed to be University), Wardha, India.
Department of Radiotherapy, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research (Deemed to be University), Wardha, India.
Front Radiol. 2025 Jun 9;5:1586440. doi: 10.3389/fradi.2025.1586440. eCollection 2025.
Bladder cancer is a malignant tumour with a high morbidity and mortality rate in the world. Moreover, it is the most prevalent as well as commonly diagnosed in older individuals, with a median age of 73 years, and it has been reported that the most frequently seen histological type of bladder cancer was urothelial carcinoma. We present a unique case of a 44-year-old female with enteric-type adenocarcinoma, a rare and aggressive bladder cancer. Her symptoms included frequent micturition (Urination) and hematuria (blood in urine), at which point she was diagnosed with High-grade urothelial carcinoma. The malignancy worsened despite cycles of treatment requiring extensive surgery. After further tests, it was found that she had urothelial carcinoma with features of intestinal tissue (tissue of the intestine) and that the disease had infiltrated into nearby blood vessels and nerves. Radiation therapy was recommended to decrease the risk of local recurrence after surgery. The challenges in treating such a patient and the positive aspects this approach can give are highlighted in a case report.
膀胱癌是一种在全球发病率和死亡率都很高的恶性肿瘤。此外，它在老年人中最为普遍且最常被诊断出，中位年龄为73岁，据报道，膀胱癌最常见的组织学类型是尿路上皮癌。我们报告一例独特的病例，一名44岁女性患有肠型腺癌，这是一种罕见且侵袭性强的膀胱癌。她的症状包括尿频（排尿）和血尿（尿液中带血），此时她被诊断为高级别尿路上皮癌。尽管经过了多次需要广泛手术的治疗周期，恶性肿瘤仍在恶化。进一步检查后发现，她患有具有肠道组织（肠组织）特征的尿路上皮癌，并且疾病已浸润到附近的血管和神经。建议进行放射治疗以降低术后局部复发的风险。一份病例报告突出了治疗此类患者的挑战以及这种方法可能带来的积极方面。
