Byrnes W C, Clarkson P M, White J S, Hsieh S S, Frykman P N, Maughan R J
J Appl Physiol (1985). 1985 Sep;59(3):710-5. doi: 10.1152/jappl.1985.59.3.710.
Perceived muscle soreness ratings, serum creatine kinase (CK) activity, and myoglobin levels were assessed in three groups of subjects following two 30-min exercise bouts of downhill running (-10 degrees slope). The two bouts were separated by 3, 6, and 9 wk for groups 1, 2, and 3, respectively. Criterion measures were obtained pre- and 6, 18, and 42 h postexercise. On bout 1 the three groups reported maximal soreness at 42 h postexercise. Also, relative increases in CK for groups 1, 2, and 3 were 340, 272, and 286%, respectively. Corresponding values for myoglobin were 432, 749, and 407%. When the same exercise was repeated, significantly less soreness was reported and smaller increases in CK and myoglobin were found for groups 1 and 2. For example, the percent CK increases on bout 2 for groups 1 and 2 were 63 and 62, respectively. Group 3 demonstrated no significant difference in soreness ratings, CK activities, or myoglobin levels between bouts 1 and 2. It was concluded that performance of a single exercise bout had a prophylactic effect on the generation of muscle soreness and serum protein responses that lasts up to 6 wk.
在三组受试者进行两次30分钟的下坡跑（坡度为-10度）运动后，评估了他们的肌肉酸痛感知评分、血清肌酸激酶（CK）活性和肌红蛋白水平。对于第1、2和3组，两次运动之间的间隔分别为3、6和9周。在运动前以及运动后6、18和42小时获取标准测量值。在第一次运动时，三组在运动后42小时报告了最大酸痛感。此外，第1、2和3组的CK相对增加量分别为340%、272%和286%。肌红蛋白的相应值分别为432%、749%和407%。当重复相同运动时，第1组和第2组报告的酸痛感明显减轻，CK和肌红蛋白的增加量也较小。例如，第1组和第2组在第二次运动时CK的增加百分比分别为63%和62%。第3组在两次运动之间的酸痛评分、CK活性或肌红蛋白水平上没有显著差异。得出的结论是，单次运动对肌肉酸痛和血清蛋白反应的产生具有预防作用，这种作用可持续长达6周。
