Markus Irit, Constantini Keren, Goldstein Nir, Amedi Roee, Bornstein Yael, Stolkovsky Yael, Vidal Merav, Lev-Ari Shahar, Balaban Roy, Leibou Stav, Blumenfeld-Katzir Tamar, Ben-Eliezer Noam, Peled David, Assaf Yaniv, Jensen Dennis, Constantini Naama, Dubnov-Raz Gal, Halperin Israel, Gepner Yftach
Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, and Sylvan Adams Sports Institute, Tel-Aviv University, Tel-Aviv, Israel.
Department of Health Promotion, School of Public Health, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Front Physiol. 2022 Jun 13;13:916924. doi: 10.3389/fphys.2022.916924. eCollection 2022.
Compare recovery rates between active young (Y) and middle-aged (MA) males up to 48H post aerobically based, exercise-induced muscle damage (EIMD) protocol. A secondary aim was to explore the relationships between changes in indices associated with EIMD and recovery throughout this timeframe. Twenty-eight Y ( = 14, 26.1 ± 2.9y, 74.5 ± 9.3 kg) and MA ( = 14, 43.6 ± 4.1y, 77.3 ± 12.9 kg) physically active males, completed a 60-min downhill running (DHR) on a treadmill at -10% incline and at 65% of maximal heart rate (HR). Biochemical, biomechanical, psychological, force production and muscle integrity (using MRI diffusion tensor imaging) markers were measured at baseline, immediately-post, and up to 48H post DHR. During the DHR, HR was lower ( < 0.05) in MA compared to Y, but running pace and distance covered were comparable between groups. No statistical or meaningful differences were observed between groups for any of the outcomes. Yet, Significant ( < 0.05) time-effects within each group were observed: markers of muscle damage, cadence and perception of pain increased, while TNF-a, isometric and dynamic force production and stride-length decreased. Creatine-kinase at 24H-post and 48H-post were correlated ( < 0.05, range = -0.57 to 0.55) with pain perception, stride-length, and cadence at 24H-post and 48H-post. Significant ( < 0.05) correlations were observed between isometric force production at all time-points and IL-6 at 48H-post DHR ( range = -0.62 to (-0.74). Y and MA active male amateur athletes recover in a comparable manner following an EIMD downhill protocol. These results indicate that similar recovery strategies can be used by trainees from both age groups following an aerobic-based EIMD protocol.
比较有氧锻炼诱导的肌肉损伤（EIMD）方案后48小时内，活跃的年轻（Y）男性和中年（MA）男性之间的恢复率。第二个目的是探讨在此时间段内，与EIMD相关的指标变化和恢复之间的关系。28名Y组（n = 14，26.1±2.9岁，74.5±9.3千克）和MA组（n = 14，43.6±4.1岁，77.3±12.9千克）身体活跃的男性，在跑步机上以-10%的坡度和最大心率（HR）的65%完成了60分钟的下坡跑（DHR）。在基线、DHR后即刻以及DHR后48小时测量生化、生物力学、心理、力量产生和肌肉完整性（使用MRI扩散张量成像）指标。在DHR期间，MA组的HR低于Y组（P < 0.05），但两组之间的跑步速度和跑过的距离相当。在任何结果方面，两组之间均未观察到统计学或有意义的差异。然而，在每组中均观察到显著的（P < 0.05）时间效应：肌肉损伤指标、步频和疼痛感知增加，而TNF-α、等长和动态力量产生以及步幅减小。DHR后24小时和48小时的肌酸激酶与DHR后24小时和48小时的疼痛感知、步幅和步频相关（P < 0.05，r范围 = -0.57至0.55）。在所有时间点的等长力量产生与DHR后48小时的IL-6之间观察到显著的（P < 0.05）相关性（r范围 = -0.62至-0.74）。Y组和MA组活跃的男性业余运动员在EIMD下坡方案后以相似的方式恢复。这些结果表明，遵循基于有氧的EIMD方案时，两个年龄组的受训者可以使用相似的恢复策略。
