Lee Wei-Hsuan, Chen Yu-Hsi, Wang Tsai-Yu, Chang Wen-Jui, Liao Ting-Wei, Hung Wei-Syun, Lin Shih-Wei, Chen Ning-Hung, Fang Ji-Tseng, Chuang Li-Pang
Department of Pulmonary and Critical Care Medicine, Sleep Center, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Sleep Breath. 2025 Jun 24;29(4):225. doi: 10.1007/s11325-025-03398-w.
Vitamin D is essential not only for skeletal health but also for regulating sleep. Recent studies suggest a link between vitamin D deficiency and poor sleep quality, including lower sleep efficiency and shorter sleep duration. This study aimed to investigate the relationship between sleep quality and serum vitamin D levels in healthy elderly individuals.
This study examined the association between serum vitamin D levels and sleep quality in individuals aged 60 years and above residing in Taipei's Health & Culture Village and Active Aging Center. A total of 465 participants were enrolled, with those exhibiting specific organ abnormalities or dysfunctions excluded. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI), and vitamin D levels were measured using enzyme-linked immunosorbent assay (ELISA). The relationships between vitamin D levels and PSQI scores were analyzed, with a focus on the daytime dysfunction component of the PSQI.
Among the seven domains of the PSQI, the daytime dysfunction domain had the strongest statistical association with serum vitamin D levels (p = 0.044). Participants without daytime dysfunction had significantly higher vitamin D levels than did those with daytime dysfunction (p = 0.04). No significant associations were detected between vitamin D levels and other factors, such as sex or age.
Higher serum vitamin D levels are associated with better sleep quality in elderly individuals, particularly in those without daytime dysfunction. This finding highlights the potential importance of maintaining adequate vitamin D levels to promote healthy sleep patterns in older adults.
维生素D不仅对骨骼健康至关重要，而且对调节睡眠也很重要。最近的研究表明维生素D缺乏与睡眠质量差之间存在联系，包括睡眠效率降低和睡眠时间缩短。本研究旨在调查健康老年人睡眠质量与血清维生素D水平之间的关系。
本研究调查了居住在台北健康与文化村及活跃老化中心的60岁及以上个体的血清维生素D水平与睡眠质量之间的关联。共招募了465名参与者，排除了那些有特定器官异常或功能障碍的人。使用匹兹堡睡眠质量指数（PSQI）评估睡眠质量，使用酶联免疫吸附测定（ELISA）测量维生素D水平。分析了维生素D水平与PSQI评分之间的关系，并重点关注PSQI的日间功能障碍部分。
在PSQI的七个领域中，日间功能障碍领域与血清维生素D水平的统计关联最强（p = 0.044）。没有日间功能障碍的参与者的维生素D水平明显高于有日间功能障碍的参与者（p = 0.04）。在维生素D水平与其他因素（如性别或年龄）之间未检测到显著关联。
较高的血清维生素D水平与老年人较好的睡眠质量相关，特别是在那些没有日间功能障碍的人中。这一发现突出了维持足够的维生素D水平以促进老年人健康睡眠模式的潜在重要性。
