Pepele M S, Aktas I, Demiroz O, Derya S, Yildirim E, Bilen M N, Demir B
Department of Emergency Medicine, Inonu University, Malatya, Turkey.
Department of Cardiology, Turgut Ozal University, School of Medicine, Malatya, Turkey.
Niger J Clin Pract. 2025 Jun 1;28(6):758-763. doi: 10.4103/njcp.njcp_417_24. Epub 2025 Jun 25.
The HEART score is a risk stratification tool for acute chest pain, evaluating history, ECG, age, risk factors, and troponin. The SYNTAX (synergy between percutaneous coronary intervention with TAXUS and cardiac surgery) score assesses the extent and complexity of coronary artery disease (CAD) and is widely used in patients undergoing coronary interventions.
To determine the relationship between the HEART and SYNTAX scores in patients with non-ST elevation myocardial infarction (NSTEMI).
A total of 222 NSTEMI patients who underwent coronary angiography were included. The HEART score was calculated at admission, and all patients underwent angiography within 12 hours. SYNTAX was used to evaluate CAD severity. Patients were divided into two groups based on SYNTAX scores. Comparisons were made according to demographic data, laboratory findings, and risk factors. Variables associated with high SYNTAX scores were identified. A P value of < 0.05 was considered statistically significant.
The mean age was 63.67 ± 11.89 years, and 74.77% of the patients were male. Patients with high SYNTAX scores had significantly higher HEART scores and more frequent diabetes and hypertension. High HEART score (OR: 3.09; 95% confidence intervals [CI]: 2.06-4.63; P < 0.001) and diabetes mellitus (OR: 4.57; 95% CI: 1.44-14.47; P = 0.010) were independently associated with high SYNTAX scores. A HEART score >7.5 predicted high SYNTAX scores with 82.1% sensitivity and 84.3% specificity (area under curve [AUC]: 0.892; P < 0.001). A strong positive correlation was found between HEART and SYNTAX scores (P < 0.001, R² =0.672).
The HEART score was significantly associated with the severity and complexity of CAD in patients with NSTEMI.
HEART评分是一种用于急性胸痛的风险分层工具，可评估病史、心电图、年龄、风险因素和肌钙蛋白。SYNTAX（紫杉醇药物洗脱支架冠状动脉介入治疗与心脏手术的协同作用）评分用于评估冠状动脉疾病（CAD）的范围和复杂性，广泛应用于接受冠状动脉介入治疗的患者。
确定非ST段抬高型心肌梗死（NSTEMI）患者中HEART评分与SYNTAX评分之间的关系。
纳入222例行冠状动脉造影的NSTEMI患者。入院时计算HEART评分，所有患者在12小时内接受造影。采用SYNTAX评分评估CAD严重程度。根据SYNTAX评分将患者分为两组。根据人口统计学数据、实验室检查结果和风险因素进行比较。确定与高SYNTAX评分相关的变量。P值<0.05被认为具有统计学意义。
平均年龄为63.67±11.89岁，74.77%的患者为男性。高SYNTAX评分患者的HEART评分显著更高，糖尿病和高血压更为常见。高HEART评分（比值比：3.09；95%置信区间[CI]：2.06 - 4.63；P < 0.001）和糖尿病（比值比：4.57；95%CI：1.44 - 14.47；P = 0.010）与高SYNTAX评分独立相关。HEART评分>7.5预测高SYNTAX评分的敏感度为82.1%，特异度为84.3%（曲线下面积[AUC]：0.892；P < 0.001）。HEART评分与SYNTAX评分之间存在强正相关（P < 0.001，R² = 0.672）。
HEART评分与NSTEMI患者CAD的严重程度和复杂性显著相关。
