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针灌洗和内镜灌洗对成年马掌指/跖趾关节及指屈肌腱鞘内微球回收的效果

Efficacy of needle and endoscopic lavage on the recuperation of microspheres from the adult equine metacarpo-/metatarsophalangeal joint and digital flexor tendon sheath.

作者信息

Beggan Christopher P, Panizzi Luca, Oliver Laurinda J

机构信息

Waikato Equine Veterinary Center, Cambridge, New Zealand.

School of Veterinary Science, Equine Veterinary Centre, Massey University, Palmerston North, New Zealand.

出版信息

Vet Surg. 2025 Aug;54(6):1157-1166. doi: 10.1111/vsu.14298. Epub 2025 Jun 25.

Abstract

OBJECTIVES

To measure microsphere recovery following needle-through-and-through lavage (NTAT) of the metacarpo-/metatarsophalangeal joint (fetlock) and digital flexor tendon sheath (DFTS) compared to endoscopic lavage (EL).

STUDY DESIGN

Ex vivo experimental study.

ANIMALS

Adult equine cadavers immediately following euthanasia (n = 10).

METHODS

Colored 15 μm microspheres (2 million) were injected into fetlock joints and DFTS. Synovial structures were assigned to NTAT or EL groups. Each lavage was performed using 5 L of 0.9% NaCl, sequentially collecting egress fluid for microsphere quantification. Recovery was compared using a full-factorial general linear model.

RESULTS

There was a significant effect of the liter of egress fluid and microsphere recovery in both fetlocks (p < .01) and DFTS (p < .01), with most microspheres recovered in the first 2 L (79%-83%) for both techniques. More microspheres were recovered in the first liter using NTAT than EL (p < .01) in both fetlocks (659 883 ± 20 820 vs. 567 601 ± 24 452) and DFTS (644 341 ± 17 460 vs. 550 637 ± 38 022). No difference in total recovered microspheres was observed between NTAT lavage of fetlock (981 600 ± 46 839) and DFTS (957 419 ± 45 729) across 5 L (p = .88).

CONCLUSION

Needle-through-and-through lavage was more effective than EL at recovering microspheres in the first liter from cadaveric equine fetlock joints and DFTS. Both techniques demonstrated comparable efficacy between fetlock and DFTS in microsphere recovery following increased lavage volumes.

CLINICAL SIGNIFICANCE

Needle-through-and-through lavage (NTAT) is a viable alternative for suspected synovial contamination when EL is delayed or not feasible. This study does not evaluate NTAT's efficacy for treating established sepsis or removing pannus/foreign bodies.

摘要

目的

与内镜灌洗(EL)相比,测量掌指/跖趾关节(球节)和指屈肌腱鞘(DFTS)进行贯穿针灌洗(NTAT)后的微球回收率。

研究设计

离体实验研究。

动物

安乐死后的成年马尸体(n = 10)。

方法

将200万个15μm的彩色微球注入球节和DFTS。滑膜结构被分配到NTAT或EL组。每次灌洗使用5L 0.9%氯化钠溶液,依次收集流出液进行微球定量。使用全因子一般线性模型比较回收率。

结果

流出液升数和微球回收率在球节(p <.01)和DFTS(p <.01)中均有显著影响,两种技术在前2L中回收的微球最多(79%-83%)。在球节(659883±20820对567601±24452)和DFTS(644341±17460对550637±38022)中,使用NTAT在第一升中回收的微球比EL更多(p <.01)。在5L的灌洗过程中,球节(981600±46839)和DFTS(957419±45729)的NTAT灌洗之间未观察到回收微球总数的差异(p =.88)。

结论

在从马尸体的球节和DFTS中回收第一升微球方面,贯穿针灌洗比EL更有效。在增加灌洗量后,两种技术在球节和DFTS的微球回收率方面显示出相当的效果。

临床意义

当EL延迟或不可行时,贯穿针灌洗(NTAT)是疑似滑膜污染的可行替代方法。本研究未评估NTAT治疗已确诊败血症或清除血管翳/异物的疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8a/12344216/a645625db859/VSU-54-1157-g002.jpg

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