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2016年至2021年中国基本药物供应与使用的趋势及差异:机构、地区和经济差异

Trends and disparity in the provision and consumption of essential medicines in China from 2016 to 2021: institutional, regional, and economic variations.

作者信息

Zhao Mingyue, Lin Chenglong, Ding Shengjie, Han Yubei, Zhao Yuhan, Gillani Ali Hassen, Fang Yu

机构信息

Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.

Center for Drug Safety and Policy Research, Xi'an Jiaotong University, Xi'an, Shaanxi, China.

出版信息

Front Public Health. 2025 Jun 10;13:1555598. doi: 10.3389/fpubh.2025.1555598. eCollection 2025.

Abstract

OBJECTIVE

Analyze the provision and consumption of essential medicines (EMs) across healthcare institutions, regions, and levels of economic development. Evaluate the mechanisms by which EMs policies promote their own implementation.

METHODS

Using national drug utilization monitoring database (2016-2021), we perform a descriptive analysis to explore trends and disparities in EM provision and consumption across three institution levels, four regions (from 30 provinces), and different economic development levels in China. Key metrics include the average number and proportion of provided EMs and the consumption rate per healthcare institution. Utilize a two-way fixed-effects regression model to evaluate the relationship between EMs provision and consumption.

FINDINGS

The average provided number of EMs is much lower than that in the national EMs list. Both provision (number and proportion) and consumption of EMs show institutional and regional disparities. There is a moderately positive correlation between EMs provided proportion and GDP (0.66,  < 0.01), while the provided proportion and consumption rate are moderately negatively correlated with GDP (-0.66,  < 0.01; -0.64,  < 0.01). In highly developed regions, EMs supply is highest but utilization lowest; in underdeveloped regions, provision is least but utilization relatively high.

CONCLUSION

This study shows disparities in EM provision and consumption across institutions, regions, and economic levels in China. Although essential medicine policy coordination with other policies needs improvement, targeted interventions are needed to bridge gaps in less developed regions and promote medicine equity.

摘要

目的

分析各级医疗机构、不同地区及不同经济发展水平下基本药物的供应与使用情况。评估基本药物政策促进自身实施的机制。

方法

利用国家药品使用监测数据库(2016 - 2021年),我们进行描述性分析,以探究中国三个机构级别、四个地区(来自30个省份)以及不同经济发展水平下基本药物供应与使用的趋势和差异。关键指标包括基本药物的平均供应数量和比例以及每个医疗机构的使用率。使用双向固定效应回归模型评估基本药物供应与使用之间的关系。

结果

基本药物的平均供应数量远低于国家基本药物目录中的数量。基本药物的供应(数量和比例)及使用均存在机构和地区差异。基本药物供应比例与国内生产总值呈中度正相关(0.66,<0.01),而供应比例和使用率与国内生产总值呈中度负相关(-0.66,<0.01;-0.64,<0.01)。在高度发达地区,基本药物供应最高但使用率最低;在欠发达地区,供应最少但使用率相对较高。

结论

本研究表明中国在各级医疗机构、不同地区及不同经济水平下基本药物的供应与使用存在差异。尽管基本药物政策与其他政策的协调需要改进,但仍需要有针对性的干预措施来缩小欠发达地区的差距并促进药品公平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/488a/12185506/43fb0fa94a1b/fpubh-13-1555598-g001.jpg

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