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鸭胚疫苗与亨普氏疫苗用于狂犬病疫苗接种的比较(作者译)

[Comparison of duck embryo vaccine and Hempt's vaccine for rabies vaccination (author's transl)].

作者信息

Merkle F, Mohr W

出版信息

MMW Munch Med Wochenschr. 1977 Apr 22;119(16):547-50.

PMID:405573
Abstract

For many years, Hempt's vaccine has been used in Germany for vaccination against rabies. In recent years the duck embryo vaccine has been gradually introduced in its place. From 1970 to 1975, 658 consultations were undertaken at the Hospital of the Tropical Institute at Hamburg because of the risk of rabies. 267 persons had to undergo vaccination, 159 of them being treated with Hempt's vaccine and 108 with duck embryo vaccine. Side effects of a more severe type were not seen in either group. Disadvantages of the duck embryo vaccine are that more individual inoculations are necessary, significantly more frequent and more persistent local and general vaccination reactions occur and that there is a delayed, possibly weaker formation of antibodies.

摘要

多年来,亨普特疫苗一直在德国用于狂犬病疫苗接种。近年来,鸭胚疫苗已逐渐取而代之。1970年至1975年期间,汉堡热带研究所医院因有感染狂犬病的风险进行了658次会诊。267人必须接种疫苗,其中159人接受亨普特疫苗治疗,108人接受鸭胚疫苗治疗。两组均未出现更严重类型的副作用。鸭胚疫苗的缺点是需要更多的个体接种,局部和全身疫苗接种反应明显更频繁、更持久,而且抗体形成延迟,可能较弱。

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MMW Munch Med Wochenschr. 1977 Apr 22;119(16):547-50.
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