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俄罗斯首次小儿面部组织次全再植经验。

First Russian Experience of Pediatric Subtotal Facial Tissue Replantation.

作者信息

Dikarev Alexey S, Vartanyan Seyran A, Martirosyan Alexander A, Zemlin Ivan A, Kudzaev Kazbek U, Sergeev Igor S, Vartanyan Robert S, Dryga Daniel U, Vlasova Irina O, Gorgoma Elen V, Bilyak Anna V, Anthoniadis Spartak S, Rudenok Daniel U, Kletshenko Elena I

机构信息

From the Maxillofacial Surgery Department, Emergency Hospital, Ministry of Health of Krasnodar Region, Krasnodar.

Maxillofacial Surgery Department, Children's State Clinical Hospital, Ministry of Health of Krasnodar Region, Krasnodar.

出版信息

Plast Reconstr Surg Glob Open. 2025 Jun 24;13(6):e6906. doi: 10.1097/GOX.0000000000006906. eCollection 2025 Jun.

DOI:10.1097/GOX.0000000000006906
PMID:40557301
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12187312/
Abstract

Treatment and rehabilitation of patients with posttraumatic, contaminated, lacerated wounds present a complex challenge. The concept of delayed, multistage treatment, as well as the rehabilitation protocols for pediatric patients is associated with a series of reconstructive procedures, one of which is face transplantation; however, it remains an unresolved issue to date due to the development of immunologic tissue intolerance by the recipient, as well as various psychosocial rehabilitation challenges. The challenge of successful pediatric replantation creates interest in the global medical community to develop generalized algorithms for managing patients with posttraumatic subtotal facial defects. This case report demonstrated the experience of the first posttraumatic subtotal facial replantation less than 12 hours after injury in a pediatric patient in Russia. The goal of this work was to show the algorithm used in the case of a pediatric posttraumatic subtotal facial defect in hopes of aiding the future development of such guidelines.

摘要

创伤后受污染撕裂伤患者的治疗与康复是一项复杂的挑战。延迟多阶段治疗的概念以及儿科患者的康复方案与一系列重建手术相关,其中之一是面部移植;然而,由于接受者出现免疫组织不耐受以及各种心理社会康复挑战,这一问题至今仍未得到解决。成功进行儿科再植的挑战引发了全球医学界对制定创伤后面部部分缺损患者综合管理算法的兴趣。本病例报告展示了俄罗斯一名儿科患者在受伤后不到12小时进行首次创伤后面部部分再植的经验。这项工作的目的是展示在儿科创伤后面部部分缺损病例中使用的算法,以期有助于此类指南的未来发展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6609/12187312/727f3d8e422b/gox-13-e6906-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6609/12187312/6ee44aea0f5c/gox-13-e6906-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6609/12187312/f5370a8511fe/gox-13-e6906-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6609/12187312/727f3d8e422b/gox-13-e6906-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6609/12187312/6ee44aea0f5c/gox-13-e6906-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6609/12187312/f5370a8511fe/gox-13-e6906-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6609/12187312/727f3d8e422b/gox-13-e6906-g003.jpg

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本文引用的文献

1
The past the present and the future of face transplantation.面部移植的过去、现在和未来。
Curr Opin Organ Transplant. 2020 Dec;25(6):568-575. doi: 10.1097/MOT.0000000000000812.
2
First Russian Experience of Composite Facial Tissue Allotransplantation.俄罗斯首例复合面部组织同种异体移植经验。
Plast Reconstr Surg Glob Open. 2019 Nov 21;7(11):e2521. doi: 10.1097/GOX.0000000000002521. eCollection 2019 Nov.
3
Total Nose and Upper Lip Replantation: A Case Report and Literature Review.全鼻及上唇再植:一例病例报告及文献综述
Plast Reconstr Surg Glob Open. 2018 Oct 3;6(10):e1839. doi: 10.1097/GOX.0000000000001839. eCollection 2018 Oct.
4
Microvascular Replantation of the Avulsed Lip.撕脱性唇的微血管再植术
J Craniofac Surg. 2018 Oct;29(7):e717-e720. doi: 10.1097/SCS.0000000000004962.
5
Ethical Issues in Pediatric Face Transplantation: Should We Perform Face Transplantation in Children?小儿面部移植中的伦理问题:我们应该对儿童进行面部移植吗?
Plast Reconstr Surg. 2016 Aug;138(2):449-454. doi: 10.1097/PRS.0000000000002387.
6
Discussion: Total Face, Eyelids, Ears, Scalp, and Skeletal Subunit Transplant: A Reconstructive Solution for the Full Face and Total Scalp Burn.讨论:全脸、眼睑、耳朵、头皮和骨骼亚单位移植:全脸和全头皮烧伤的重建解决方案。
Plast Reconstr Surg. 2016 Jul;138(1):220-221. doi: 10.1097/PRS.0000000000002303.
7
Facial fractures from dog bite injuries.犬咬伤导致的面部骨折。
Plast Reconstr Surg. 2002 Apr 1;109(4):1259-65. doi: 10.1097/00006534-200204010-00008.