Turekulova Aigerim, Dzhardemaliyeva Nurzhamal, Mereke Alibek, Kulimbet Mukhtar
School of General Medicine, Asfendiyarov Kazakh National Medical University, 050012 Almaty, Kazakhstan.
International Faculty, Asfendiyarov Kazakh National Medical University, 050012 Almaty, Kazakhstan.
Clin Pract. 2025 Jun 6;15(6):108. doi: 10.3390/clinpract15060108.
Hypertensive disorders of pregnancy, including pre-eclampsia and eclampsia, are leading causes of maternal morbidity and mortality worldwide and in Kazakhstan. This study aims to assess the burden of hypertensive disorders of pregnancy and main maternal disorders in Almaty, Kazakhstan, using the disability adjusted life years (DALY) methodology. : We conducted a retrospective analysis of women aged 18 and above in Almaty, Kazakhstan, from 2018 to 2020. The medical claim data were retrieved from the Almaty city branch of the Republican Center for Electronic Health Care. Incidence-based DALY were calculated. : The total DALY increased for severe pre-eclampsia from 109.3 in 2018 to 187.2 in 2020 per 100,000 population and eclampsia from 3.1 in 2018 to 159.3 in 2020 per 100,000 population. Also, the 25-29 years age group had the largest increase in percent change (5.8) in the total DALY for hypertensive disorders of pregnancy. In addition, the 20-24 years age groups had the largest increase in percent change in the total DALY for severe pre-eclampsia (25.8) and eclampsia (80.5). : Our findings highlight an increase in the burden of maternal disorders, especially for severe pre-eclampsia and eclampsia, in Almaty, Kazakhstan, from 2018 to 2020. Younger women bear a significant share of this burden, compounded by the pandemic's impact on healthcare services.
妊娠高血压疾病，包括先兆子痫和子痫，是全球及哈萨克斯坦孕产妇发病和死亡的主要原因。本研究旨在采用伤残调整生命年（DALY）方法评估哈萨克斯坦阿拉木图妊娠高血压疾病和主要孕产妇疾病的负担。：我们对2018年至2020年哈萨克斯坦阿拉木图18岁及以上女性进行了回顾性分析。医疗索赔数据取自共和电子医疗中心阿拉木图市分支机构。计算了基于发病率的DALY。：每10万人口中，重度先兆子痫的总DALY从2018年的109.3增加到2020年的187.2，子痫从2018年的3.1增加到2020年的159.3。此外，25 - 29岁年龄组妊娠高血压疾病的总DALY百分比变化增幅最大（5.8）。另外，20 - 24岁年龄组重度先兆子痫（25.8）和子痫（80.5）的总DALY百分比变化增幅最大。：我们的研究结果突出表明，2018年至2020年期间，哈萨克斯坦阿拉木图孕产妇疾病负担有所增加，尤其是重度先兆子痫和子痫。年轻女性承担了这一负担的很大一部分，疫情对医疗服务的影响更是雪上加霜。
