Leiva-Gea Luis, Lendínez-Jurado Alfonso, Sánchez-Palomino Paulino, Delgado-Ramos Bendición, Corte-Torres María Daniela, Leiva-Gea Isabel, Leiva-Gea Antonio
Clínicas ClearDent, 23006 Jaén, Spain.
Facultad de Odontología, Universidad de Murcia, 30003 Murcia, Spain.
Biomimetics (Basel). 2025 Jun 10;10(6):386. doi: 10.3390/biomimetics10060386.
Bone resorption following tooth loss poses significant challenges for dental implant success. Guided bone regeneration (GBR) techniques, particularly in vertically deficient ridges, often require complex procedures and soft tissue management. This case report introduces a modified occlusive barrier with a window, combined with tricalcium phosphate, to address these challenges.
A 26-year-old female with significant bone loss in the mandibular anterior region underwent GBR using a digitally designed titanium occlusive barrier. The barrier was fabricated using CAD/CAM technology and secured with screws. A blood clot mixed with tricalcium phosphate was used to promote bone regeneration. Postoperative care included regular irrigation, de-epithelialization, and follow-up over six months. Implant placement and histological analysis were performed to evaluate outcomes.
The patient achieved 8.8 mm of vertical and 7.6 mm of horizontal bone regeneration. Histological analysis confirmed the presence of mature, mineralized bone, and keratinized gingiva. The implant was successfully placed, and a fixed prosthesis was restored after four months, with stable results at a three-year follow-up.
This technique demonstrates effective bone and soft tissue regeneration in a single procedure, eliminating the need for autologous bone grafts and secondary surgeries. The use of a digitally designed occlusive barrier offers precision, reduces morbidity, and simplifies the surgical process, suggesting a promising advancement in GBR. Further studies are needed to validate these findings.
牙齿缺失后的骨吸收对牙种植体的成功构成重大挑战。引导骨再生（GBR）技术，尤其是在垂直骨量不足的牙槽嵴中，通常需要复杂的操作和软组织管理。本病例报告介绍了一种带有窗口的改良封闭屏障，结合磷酸三钙，以应对这些挑战。
一名26岁下颌前部骨量严重缺失的女性接受了使用数字设计的钛质封闭屏障的GBR治疗。该屏障采用CAD/CAM技术制作并用螺钉固定。使用与磷酸三钙混合的血凝块促进骨再生。术后护理包括定期冲洗、去上皮化以及六个月的随访。进行种植体植入和组织学分析以评估结果。
患者实现了8.8毫米的垂直骨再生和7.6毫米的水平骨再生。组织学分析证实存在成熟的矿化骨和角化牙龈。成功植入种植体，四个月后修复了固定义齿，三年随访结果稳定。
该技术在单一操作中展示了有效的骨和软组织再生，无需自体骨移植和二次手术。使用数字设计的封闭屏障提供了精确性，降低了发病率，并简化了手术过程，表明GBR有了有前景的进展。需要进一步研究来验证这些发现。
