Lei Quanxing, Wang Ziming, Yao Shuangyan, Lin Aili, Zhang Yunhui, Sun Chengxian, Liu Xiaoguang, Du Mengfang, Liu Xiaoming, An Shiheng
Henan International Laboratory for Green Pest Control, College of Plant Protection, Henan Agricultural University, Zhengzhou 450046, China.
Henan International Joint Laboratory of Taxonomy and Systematic Evolution of Insecta, Henan Institute of Science and Technology, Xinxiang 453003, China.
Insects. 2025 Jun 13;16(6):624. doi: 10.3390/insects16060624.
The ladybird beetle, , is an oligophagous pest with significant economic impact. This pest causes considerable economic damage on numerous Solanaceae crops. Neuropeptides, along with their designated receptors, play a pivotal role in regulating diverse biological processes in insects, presenting a promising avenue for innovative pest management strategies. Herein, the transcriptome of the central nervous system (CNS) of was sequenced. Overall, our analysis identified 58 neuropeptide precursor genes, from which 98 diverse mature peptides were predicted. Furthermore, 31 neuropeptide receptor genes belonging to three distinct classes were discovered, along with predictions for their potential ligands. Moreover, the expression patterns of these 58 neuropeptide genes across larval brain tissue, ventral nerve cord, and gut were evaluated using quantitative real-time PCR. Collectively, these findings will significantly contribute to future research focused on understanding the physiological functions and pharmacological characteristics of neuropeptides and their receptors in . Ultimately, these insights may facilitate the development of targeted neuropeptide-based solutions for managing this pest affecting solanaceous plants.
茄二十八星瓢虫是一种多食性害虫，具有重大经济影响。这种害虫对众多茄科作物造成了相当大的经济损害。神经肽及其特定受体在调节昆虫的各种生物过程中起着关键作用，为创新的害虫管理策略提供了一条有前景的途径。在此，对茄二十八星瓢虫中枢神经系统（CNS）的转录组进行了测序。总体而言，我们的分析鉴定出58个神经肽前体基因，从中预测出98种不同的成熟肽。此外，还发现了属于三个不同类别的31个神经肽受体基因，以及对其潜在配体的预测。此外，使用定量实时PCR评估了这58个神经肽基因在幼虫脑组织、腹神经索和肠道中的表达模式。总的来说，这些发现将对未来旨在了解茄二十八星瓢虫中神经肽及其受体的生理功能和药理学特性的研究做出重大贡献。最终，这些见解可能有助于开发基于神经肽的针对性解决方案，以管理这种影响茄科植物的害虫。
