de Morais Castro Kenes Leonel, Rohloff Júnior Nilton, Santos Elaine Talita, Valentim Jean Kaique, Garcia Rodrigo Garófallo, Rieger Giancarlo, Sgavioli Sarah
Postgraduate Program in Animal Production (PMPPA), Brazil University, Av. Hilário de Silva Passos, 950, Parque Universitário, Descalvado, São Paulo 13690-000, Brazil.
Postgraduate Program in Animal Science (PPGCA), Western Paraná State University (UNIOESTE), Rua Pernambuco, 1777, Centro, Marechal Cândido Rondon 85960-000, Brazil.
Vet Sci. 2025 Jun 13;12(6):581. doi: 10.3390/vetsci12060581.
This study evaluated the effects of zootechnical additives in combination with antibiotic growth promoters (AGPs) on broiler performance, leukocyte differential activity, phagocytic activity, intestinal histomorphometry, and the inside index. A total of 1400 one-day-old Cobb 500 male chicks were assigned to a completely randomized design with seven treatments and eight replicates of 25 birds per unit. The treatments included a basal diet without AGPs, a basal diet with AGPs, and AGPs combined with different zootechnical additives: prebiotics (fructooligosaccharides, galactooligosaccharides, beta-glucans, and mannan-oligosaccharides), probiotics ( LFU160), essential oils (cashew nut shell liquid), and organic acids (butyric acid glycerides). The results showed the treatments combining AGPs and zootechnical additives had better effects ( < 0.05) on weight gain, feed intake, the feed conversion ratio, and the productive efficiency index. The phagocytic activity was worse in birds without AGPs and with AGPs but without additives. However, birds that received AGPs in combination with zootechnical additives exhibited a poorer intestinal histomorphometry and lower inside index compared to those fed only AGPs or diets without AGPs. In conclusion, zootechnical additives can be used alongside AGPs to enhance broiler performance and immune function, particularly during early growth stages, with essential oils showing the most promising results.
本研究评估了畜牧技术添加剂与抗生素生长促进剂（AGPs）联合使用对肉鸡生产性能、白细胞分类活性、吞噬活性、肠道组织形态计量学和内脏指数的影响。总共1400只1日龄的科宝500雄性雏鸡被分配到完全随机设计中，有7种处理，每个单元25只鸡，重复8次。处理包括不含AGPs的基础日粮、含AGPs的基础日粮，以及AGPs与不同畜牧技术添加剂的组合：益生元（低聚果糖、低聚半乳糖、β-葡聚糖和甘露寡糖）、益生菌（LFU160）、精油（腰果壳液）和有机酸（丁酸甘油酯）。结果表明，AGPs与畜牧技术添加剂联合使用的处理在体重增加、采食量、饲料转化率和生产效率指数方面有更好的效果（<0.05）。在不含AGPs以及含AGPs但不含添加剂的鸡中，吞噬活性较差。然而，与仅饲喂AGPs或不含AGPs日粮的鸡相比，接受AGPs与畜牧技术添加剂组合的鸡肠道组织形态计量学较差，内脏指数较低。总之，畜牧技术添加剂可与AGPs一起使用，以提高肉鸡的生产性能和免疫功能，特别是在生长早期阶段，精油显示出最有前景的结果。
