Yan Juping, Wu Xiayang, Dong Ke, Zhang Zhiyuan, Sun Xuejun, Gao Shaopeng, Liu Jinxian, Chai Baofeng
School of Environmental and Resource, Taiyuan University of Science and Technology, Taiyuan 030024, China.
School of Environmental and Resource Sciences, Shanxi University, Taiyuan 030006, China.
Toxics. 2025 May 22;13(6):422. doi: 10.3390/toxics13060422.
Antibiotic contamination and its environmental impact in water-scarce and human activity-intensive regions have been poorly researched, particularly in the Zhuozhang River, China. Thus, this study investigated the occurrence, sources, and ecological risks of 27 different antibiotics in the Zhuozhang River, based on water samples collected from representative locations including major reservoirs, upstream of the river, the main river channel, and a wastewater treatment plant (WWTP). Results showed widespread contamination by quinolones, with concentrations ranged from 41.7 to 184.3 ng/L. Quinolones-particularly ofloxacin and cinoxacin-were identified as posing moderate ecological risks, with heightened concerns in the main river channel and wastewater treatment plant areas. Source apportionment using the positive matrix factorization model identified livestock farming as the dominant contributor to antibiotic pollution, accounting for 22.9% of the total antibiotic load in the river. These findings underscore the urgency of enhancing monitoring and management strategies to mitigate antibiotic contamination, especially in high-risk areas such as wastewater treatment plants and main river sections.
在水资源稀缺且人类活动密集的地区，抗生素污染及其对环境的影响一直缺乏深入研究，在中国的浊漳河地区尤为如此。因此，本研究基于从包括主要水库、河流上游、主河道和污水处理厂等代表性地点采集的水样，调查了浊漳河中27种不同抗生素的存在情况、来源及生态风险。结果表明喹诺酮类抗生素污染广泛，浓度范围为41.7至184.3纳克/升。喹诺酮类抗生素，特别是氧氟沙星和西诺沙星，被确定为具有中等生态风险，在主河道和污水处理厂区域尤为令人担忧。使用正定矩阵因子分解模型进行源解析发现，畜牧业是抗生素污染的主要来源，占河流中抗生素总负荷的22.9%。这些发现凸显了加强监测和管理策略以减轻抗生素污染的紧迫性，特别是在污水处理厂和主要河段等高风险地区。
