Willemze R, Scheffer E
J Am Acad Dermatol. 1985 Sep;13(3):418-28. doi: 10.1016/s0190-9622(85)70183-1.
The relationship between lymphomatoid papulosis and pityriasis lichenoides is a matter of considerable debate. Differentiation between these two conditions is, however, important because patients with lymphomatoid papulosis, unlike those with pityriasis lichenoides, may develop systemic lymphoma and thus require long-term follow-up. In our study the clinical and histologic features of eighty-two patients with pityriasis lichenoides and twenty-six patients with lymphomatoid papulosis were reviewed and compared. Clinical and histologic differences were recognized, not only allowing differentiation between the two conditions, but also suggesting that they are pathogenetically distinct diseases. Finally, evidence is presented to suggest that the different views on the relationship between these diseases mainly result from differences in patient selection.
淋巴瘤样丘疹病与苔藓样糠疹之间的关系是一个备受争议的问题。然而,区分这两种疾病很重要,因为与苔藓样糠疹患者不同,淋巴瘤样丘疹病患者可能会发展为系统性淋巴瘤,因此需要长期随访。在我们的研究中,回顾并比较了82例苔藓样糠疹患者和26例淋巴瘤样丘疹病患者的临床和组织学特征。认识到了临床和组织学差异,这不仅有助于区分这两种疾病,还表明它们在发病机制上是不同的疾病。最后,有证据表明,对这些疾病之间关系的不同观点主要源于患者选择的差异。