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佛罗里达州在冠状病毒大流行之前及期间酒精类洗手液摄入事件的发生率和特征

Incidence and Characteristics of Alcohol-Based Hand Sanitizer Ingestion in Florida before and during the Coronavirus Pandemic.

作者信息

Arnold Justin, Athanasios Amira, Nguyen Diep, Mhaskar Rahul

机构信息

University of South Florida, Department of Emergency Medicine, Tampa, Florida.

Hackensack Meridian Jersey Shore University Medical Center, Department of Psychiatry, Neptune, New Jersey.

出版信息

West J Emerg Med. 2025 Mar 24;26(3):643-649. doi: 10.5811/westjem.20814.

Abstract

INTRODUCTION

Hand sanitizer use and media coverage increased throughout the coronavirus-2019 pandemic. In this study our goal was to examine and compare the incidence, demographics, and clinical outcomes of exposures to alcohol-based hand sanitizers (ABHS) before and during the COVID-19 pandemic in the state of Florida.

METHODS

We analyzed statewide data on all ABHS exposures in adults collected by the Florida Poison Information Network from March 1, 2015-February 28, 2020 ("pre-COVID-19" cohort) and during the COVID-19 pandemic from March 1, 2020-May 5, 2023 ("COVID-19" cohort). We performed descriptive, univariable, and multivariable analyses to assess changes in sex, age, medical outcome, and intentionality of the exposure in the pre-COVID-19 vs COVID-19 study periods, and we examined the factors associated with medical outcomes.

RESULTS

We identified 876 single-substance ingestions of ABHS, 414 in the pre-COVID-19 cohort and 462 in the COVID-19 cohort. The proportions of ABHS ingestions increased significantly during the COVID-19 pandemic in all age groups except the 25-50 age group, where it decreased. Individuals 18-24 of age and those ≥51 years showed a relative increase in both intentional and unintentional ingestions during the COVID-19 period compared to the 25-50 age group. The significant risk factors associated with more severe outcomes in exposed individuals were intentional exposures and younger age.

CONCLUSION

Unintentional ingestions of alcohol-based hand sanitizers showed a relative increase during the COVID-19 pandemic, particularly in individuals 18-25 years of age and those ≥51. Both intentional ingestions and younger age increased the likelihood of moderate or severe outcomes. Harm reduction strategies targeted toward younger individuals and those with intentional ingestions should be considered during future pandemics.

摘要

引言

在2019年冠状病毒大流行期间,洗手液的使用和媒体报道都有所增加。在本研究中,我们的目标是检查和比较佛罗里达州在2019冠状病毒病大流行之前和期间酒精类洗手液(ABHS)暴露的发生率、人口统计学特征和临床结果。

方法

我们分析了佛罗里达中毒信息网络收集的2015年3月1日至2020年2月28日(“COVID-19之前”队列)以及2020年3月1日至2023年5月5日COVID-19大流行期间(“COVID-19”队列)所有成人ABHS暴露的全州数据。我们进行了描述性、单变量和多变量分析,以评估COVID-19之前与COVID-19研究期间暴露的性别、年龄、医疗结果和暴露意图的变化,并研究与医疗结果相关的因素。

结果

我们确定了876例ABHS单一物质摄入病例,其中COVID-19之前队列中有414例,COVID-19队列中有462例。除25至50岁年龄组摄入量下降外,COVID-19大流行期间所有年龄组的ABHS摄入量比例均显著增加。与25至50岁年龄组相比,18至24岁个体和51岁及以上个体在COVID-19期间有意和无意摄入均相对增加。暴露个体中与更严重结果相关的显著风险因素是有意暴露和年龄较小。

结论

在COVID-19大流行期间,酒精类洗手液的无意摄入相对增加,尤其是在18至25岁个体和51岁及以上个体中。有意摄入和年龄较小都会增加出现中度或严重结果的可能性。在未来大流行期间,应考虑针对年轻个体和有意摄入者的减少伤害策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/347e/12208005/807c4ec6158e/wjem-26-643-g001.jpg

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