Toy Jake, Lauer Caroline, Kaji Amy H, Thomas Joseph L, Megowan Nichelle, Bosson Nichole, Gausche-Hill Marianne, Dhawan Puneet, Kloner Robert A, Rasnake Sara, French William, Schlesinger Shira
Los Angeles Emergency Medical Services Agency, Santa Fe Springs, California.
Harbor-UCLA Medical Center, Department of Emergency Medicine, Torrance, California.
West J Emerg Med. 2025 May 20;26(3):729-736. doi: 10.5811/westjem.35271.
The use of coronary artery bypass grafting (CABG) for primary revascularization during the acute care of ST-elevation myocardial infarction (STEMI) patients has declined significantly in the past decade; but there is little data to determine whether there has been a change in the use of CABG for STEMI patients treated by emergency medical services (EMS). In this study we described the incidence of urgent or emergent CABG for STEMI patients treated in a large, regionalized cardiac care system.
We obtained data obtained for patients transported by EMS between January 2011-December 2022 who were diagnosed with acute STEMI on prehospital or emergency department (ED) electrocardiogram and taken for primary diagnostic catheterization. All STEMI patients were transported by EMS to one of 34 STEMI receiving centers (SRC) in a regionalized cardiac care system, all of which are required to maintain onsite cardiac surgery as a condition of their SRC designation. Patients were considered to have undergone urgent or emergent CABG if it was performed within 72 hours of the primary diagnostic cardiac catheterization. We excluded patients if no diagnostic catheterization was performed or if CABG was performed >72 hours after diagnostic catheterization. The primary outcome was the incidence of urgent or emergent CABG. Patients were further stratified by time between diagnostic catheterization and CABG (<24 hours, 24-48 hours, 48-72 hours).
A total of 28,349 patients were transported by EMS and diagnosed with an acute STEMI during the study period. Only 384 (1.35%) patients underwent CABG within 72 hours of diagnostic catheterization: 268 (0.95%) underwent CABG in <24 hours; 71 (0.25%) in 24-48 hours, and 45 (0.16%) in 48-72 hours. The median age of patients undergoing CABG was 64 years (interquartile range 58-72). Twenty-eight (7.3%) experienced prehospital cardiac arrest, and eight (2.1%) required vasopressors. Prior to undergoing CABG, 137 patients (36%) underwent primary percutaneous coronary intervention. The proportion of patients undergoing CABG within 72 hours remained relatively stable between 2011-2022 at 1.19% and 1.96%, respectively.
Urgent or emergent CABG remained infrequently performed for acute STEMI patients after primary diagnostic catheterization. There was little change in the percentage of STEMI patients who received CABG within 72 hours of diagnostic catheterization over the past decade. These findings suggest that regional or local policies requiring on-site cardiac surgery at SRCs may be reconsidered.
在过去十年中,冠状动脉旁路移植术(CABG)用于ST段抬高型心肌梗死(STEMI)患者急性治疗期间的初次血运重建的情况已显著减少;但几乎没有数据能确定紧急医疗服务(EMS)治疗的STEMI患者使用CABG的情况是否发生了变化。在本研究中,我们描述了在一个大型的、区域化心脏护理系统中接受治疗的STEMI患者进行紧急或急诊CABG的发生率。
我们获取了2011年1月至2022年12月期间由EMS转运的患者的数据,这些患者在院前或急诊科(ED)心电图上被诊断为急性STEMI,并接受了初次诊断性心导管检查。所有STEMI患者均由EMS转运至区域化心脏护理系统中的34个STEMI接收中心(SRC)之一,所有这些中心都被要求将现场心脏手术作为其SRC指定的条件。如果在初次诊断性心导管检查后72小时内进行了CABG,则认为患者接受了紧急或急诊CABG。如果未进行诊断性心导管检查或CABG在诊断性心导管检查后超过72小时进行,我们将排除这些患者。主要结局是紧急或急诊CABG的发生率。患者还根据诊断性心导管检查和CABG之间的时间(<24小时、24 - 48小时、48 - 72小时)进行了进一步分层。
在研究期间,共有28349例患者由EMS转运并被诊断为急性STEMI。只有384例(1.35%)患者在诊断性心导管检查后72小时内接受了CABG:268例(0.95%)在<24小时内接受了CABG;71例(0.25%)在24 - 48小时内接受了CABG,45例(0.16%)在48 - 72小时内接受了CABG。接受CABG的患者的中位年龄为64岁(四分位间距58 - 72)。28例(7.3%)经历了院前心脏骤停,8例(2.1%)需要使用血管升压药。在接受CABG之前,137例患者(36%)接受了初次经皮冠状动脉介入治疗。2011年至2022年间,在诊断性心导管检查后72小时内接受CABG的患者比例分别保持在1.19%和1.96%之间,相对稳定。
在初次诊断性心导管检查后,急性STEMI患者很少进行紧急或急诊CABG。在过去十年中,在诊断性心导管检查后72小时内接受CABG的STEMI患者百分比几乎没有变化。这些发现表明,可能需要重新考虑要求SRC进行现场心脏手术的区域或地方政策。