van Rooij W J, Sluzewski M
Algemeen Ziekenhuis Turnhout, Rubensstraat 166, Turnhout, 2300, Belgium.
Acta Neurol Belg. 2025 Jun 26. doi: 10.1007/s13760-025-02830-y.
PhotBioModulation Therapy (PBMT) is regarded as a safe therapy for various disorders. We report a patient with a vertebral artery dissection treated with PBMT resulting in a poor neurological outcome.
A 69-year-old patient with a PICA infarction after a vertebral artery dissection was treated with PhotoBioModulation Therapy using a helmet. This therapy induces strong vasodilatation in the area of application. Shortly after this treatment, she fell asleep and did not wake up the next morning. Clinically she was comatose and an MRI showed bithalamic and mesencephalic infarction as a result of thrombosis of the basilar artery tip. A causative relation between the PhotoBioModulation Therapy and the poor outcome is likely based on the time course, the immediate complaints after treatment, and the usually excellent prognosis after vertebral artery dissection.
We advise the manufacturers of PBMT devices to add (recent) stroke to the list of contraindications.
光生物调节疗法（PBMT）被认为是一种治疗各种疾病的安全疗法。我们报告了一名接受PBMT治疗的椎动脉夹层患者，其神经功能预后较差。
一名69岁的患者在椎动脉夹层后发生小脑后下动脉梗死，使用头盔进行光生物调节治疗。这种疗法在应用区域引起强烈的血管扩张。治疗后不久，她入睡，第二天早上没有醒来。临床上她处于昏迷状态，磁共振成像显示基底动脉尖血栓形成导致双侧丘脑和中脑梗死。基于时间进程、治疗后的即时症状以及椎动脉夹层后通常良好的预后，光生物调节疗法与不良预后之间可能存在因果关系。
我们建议PBMT设备制造商将（近期）中风添加到禁忌症列表中。
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