Ahmad Suhail, Rabbani Shaik, Salma Umme, Khan Salman A
Department of Chemistry, School of Sciences, Maulana Azad National Urdu University, Hyderabad, 500032, Telangana, India.
J Fluoresc. 2025 Jun 26. doi: 10.1007/s10895-025-04401-z.
Mercury contamination poses a significant environmental and health hazard due to its high toxicity and bioaccumulative nature. The development of highly selective and sensitive sensors for Hg ion detection has gained immense research interest. Among various chemosensors, imidazole-based fluorescent sensors have emerged as promising moiety due to their unique electronic properties, strong metal-binding affinity, and tunable fluorescence response. This review comprehensively explores the recent advancements in imidazole-functionalized fluorescent probes for Hg⁺ sensing, highlighting different design strategies, sensing mechanisms, and structure-property relationships. This review comprehensively summarizes recent progress in the design and development of imidazole-based fluorescent probes for Hg⁺ detection. Various sensing mechanisms including fluorescence quenching (OFF), fluorescence enhancement (ON), and ratiometric approaches are discussed in relation to their molecular design and structure-property correlations. The analytical performance of these probes is evaluated in terms of sensitivity, selectivity, response time, and applicability in complex sample matrices.
汞污染因其高毒性和生物累积性而对环境和健康构成重大危害。开发用于汞离子检测的高选择性和灵敏传感器已引起了极大的研究兴趣。在各种化学传感器中，基于咪唑的荧光传感器因其独特的电子性质、强大的金属结合亲和力和可调谐的荧光响应而成为有前景的部分。本综述全面探讨了用于汞离子传感的咪唑功能化荧光探针的最新进展，重点介绍了不同的设计策略、传感机制以及结构-性能关系。本综述全面总结了用于汞离子检测的基于咪唑的荧光探针设计与开发的最新进展。讨论了各种传感机制，包括荧光猝灭（关）、荧光增强（开）和比率法，并涉及其分子设计和结构-性能相关性。根据灵敏度、选择性、响应时间以及在复杂样品基质中的适用性对这些探针的分析性能进行了评估。
