Sadia Maria, Khan Jehangir, Khan Rizwan, Shah Syed Wadood Ali, Zada Adil, Zahoor Muhammad, Ullah Riaz, Ali Essam A
Department of Chemistry, University of Malakand, Chakdara 18800, Lower Dir, Khyber Pakhtunkhwa, Pakistan.
Department of Electrical Engineering, Kwangwoon University, Seoul 54047, South Korea.
ACS Omega. 2023 Jul 19;8(30):27500-27509. doi: 10.1021/acsomega.3c03131. eCollection 2023 Aug 1.
The presence of an abnormal amount of Ni in the human body causes various health issues. Therefore, this work aimed to synthesize the curcumin-based fluorescence-on sensor [2,6-bis(()-4-chlorobenzylidene)-cyclohexan-1-one] that was capable of selectively responding to Ni ions in aqueous solution. The structure of was confirmed by H NMR and Fourier transform infrared (FTIR) spectroscopy. The Ni ion sensing was based on the fluorescence enhancement of the fluorophore () in neutral aqueous medium. The response of the -based sensor was highly selective toward Ni ions, whereas the possible interferences from other metal cations were negligible. had a fast response; it was selective and had a sensitive detection limit (LOD = 2 × 10 M) toward Ni ions in neutral medium with a high association constant () value of 3.6 × 10 M for the complex formation between the and Ni ions. Job's plot and DFT calculations proved that the binding stoichiometry of for Ni was 2:1. was recovered using EDTA as a chelating agent after being employed as a fluorescent sensor. These characteristics ensured the potential use of as a new class of chemosensor for environmental applications.
人体中镍含量异常会引发各种健康问题。因此，本研究旨在合成基于姜黄素的荧光开启型传感器[2,6 - 双（（） - 4 - 氯亚苄基） - 环己酮 - 1]，该传感器能够在水溶液中对镍离子进行选择性响应。通过核磁共振氢谱（H NMR）和傅里叶变换红外光谱（FTIR）对其结构进行了确认。镍离子传感基于荧光团（）在中性水介质中的荧光增强。基于该传感器对镍离子具有高度选择性，而其他金属阳离子的可能干扰可忽略不计。该传感器响应迅速；在中性介质中对镍离子具有选择性且检测限灵敏（检测限 = 2×10 M），与镍离子形成配合物的缔合常数（）值高达3.6×10 M。Job曲线和密度泛函理论（DFT）计算证明该传感器与镍的结合化学计量比为2:1。在用作荧光传感器后，使用乙二胺四乙酸（EDTA）作为螯合剂可回收该传感器。这些特性确保了该传感器作为一类新型化学传感器在环境应用中的潜在用途。
