Cama I Gibernau Elisenda, Aglanu Leslie Mawuli, Zakane Alphonse, Dekker Denise, Jahn Albrecht, Sié Ali, Amuasi John Humphrey, Souares Aurélia
Heidelberg Institute of Global Health, Heidelberg University Hospital, Im Neuenheimer Feld 130.3, Heidelberg, Germany.
Kumasi Centre for Collaborative Research in Tropical Medicine, Kumasi, Ghana.
Antimicrob Resist Infect Control. 2025 Jun 25;14(1):72. doi: 10.1186/s13756-025-01594-7.
Antimicrobial resistance (AMR) is a global health concern, particularly in low- and middle-income countries. As human behaviour plays a crucial role in the emergence and spread of resistance, data on the understanding of AMR awareness are very important for assessing the situation and developing effective interventions. The aim of this study was to analyse the knowledge, attitudes and practices (KAP) related to antibiotics and awareness towards antibiotic resistance among community members in two districts in Ghana, and Burkina Faso.
A cross-sectional survey was used to collect data on socio-demographic, economic factors, and KAP. In Burkina Faso a simple randomization was carried out, whereas in Ghana we performed a double-stage randomization. The data was collected using an electronic data capture between February and March 2023 in Ghana, and from July to November 2023 in Burkina Faso. Data analysis employed descriptive statistics, and logistic regressions.
A total of 1,114 participants in Ghana and 1,011 in Burkina Faso were included. The majority knew the term "Antibiotic" (Ghana: n = 687, 61.67%; Burkina Faso: n = 767, 75.87%), but only a minority were aware of AMR (Ghana: n = 381, 34.2%; Burkina Faso: n = 270, 26.71%). In both countries, participants had a middle level of knowledge about antibiotics (Ghana: n = 597; 53.59%, Burkina Faso: n = 502, 49.65%), positive attitudes towards antibiotic utilization (Ghana: n = 702, 63.02%; Burkina Faso: n = 510, 50.45%), and most of them reported a responsible use of antibiotics (Ghana: n = 875, 78.55%; Burkina Faso: n = 713, 70.52%).
Despite familiarity with antibiotics, self-reported responsible use did not align with actual observed behaviours in both countries. Additionally, a significant lack of awareness about AMR highlights the need for a targeted educational intervention to enhance understanding of its risks and increase appropriate practices.
抗菌药物耐药性（AMR）是一个全球卫生问题，在低收入和中等收入国家尤为突出。由于人类行为在耐药性的出现和传播中起着关键作用，关于抗菌药物耐药性认知的相关数据对于评估形势和制定有效干预措施非常重要。本研究的目的是分析加纳和布基纳法索两个地区社区成员对抗生素的知识、态度和实践（KAP）以及对抗生素耐药性的认识。
采用横断面调查收集社会人口统计学、经济因素以及KAP方面的数据。在布基纳法索进行简单随机抽样，而在加纳进行两阶段随机抽样。数据于2023年2月至3月在加纳、2023年7月至11月在布基纳法索通过电子数据采集方式收集。数据分析采用描述性统计和逻辑回归。
加纳共纳入1114名参与者，布基纳法索共纳入1011名参与者。大多数人知道“抗生素”这个词（加纳：n = 687，61.67%；布基纳法索：n = 767，75.87%），但只有少数人了解抗菌药物耐药性（加纳：n = 381，34.2%；布基纳法索：n = 270，26.71%）。在两个国家，参与者对抗生素的知识水平中等（加纳：n = 597；53.59%，布基纳法索：n = 502，49.65%），对抗生素使用持积极态度（加纳：n = 702，63.02%；布基纳法索：n = 510，50.45%），并且大多数人报告对抗生素的使用是负责任的（加纳：n = 875，78.55%；布基纳法索：n = 713，70.52%）。
尽管熟悉抗生素，但在两个国家，自我报告的负责任使用情况与实际观察到的行为并不一致。此外，对抗菌药物耐药性的认识严重不足，凸显了有针对性的教育干预的必要性，以增强对其风险的理解并增加适当的实践。
