Cunningham D A, Nancekievill E A, Paterson D H, Donner A P, Rechnitzer P A
J Gerontol. 1985 Nov;40(6):703-7. doi: 10.1093/geronj/40.6.703.
The ventilation threshold (VeT) in 60 healthy men ages 22 to 65 years was determined on a maximal treadmill test. The VeT was identified as the highest VO2 before the ventilatory equivalent for oxygen began to increase without a corresponding increase in the ventilatory equivalent for carbon dioxide. The VO2 max was significantly lower in the 60 compared with the 20-year-old group (with age, r = -.81). The VeT was significantly lower in the oldest compared with the youngest group (with age, r = -.69); however, the VeT as a percentage of VO2 max was significantly greater in the oldest group, (with age, r = .37). The reserve capacity (VO2 max minus VeT) was significantly lower in the older men (with age, r = -.75) and was due to a greater reduction in VO2 max than in VeT. With multiple regression analysis, the variability in VeT was determined primarily by VO2 max (65.8%) and not age. Decrease in strenuous activity with age may account for the large reduction in VO2 max, whereas maintained submaximal activity may attenuate the reduction in VO2 at the ventilation threshold, thus resulting in a large loss in functional reserve above the level of the VeT.
在一项最大运动平板试验中，测定了60名年龄在22至65岁之间的健康男性的通气阈值（VeT）。VeT被确定为在氧通气当量开始增加而二氧化碳通气当量没有相应增加之前的最高摄氧量（VO2）。与20岁组相比，60岁组的最大摄氧量（VO2 max）显著降低（年龄与VO2 max的相关系数r = -0.81）。与最年轻组相比，最年长组的VeT显著降低（年龄与VeT的相关系数r = -0.69）；然而，最年长组中VeT占VO2 max的百分比显著更高（年龄与该百分比的相关系数r = 0.37）。老年男性的储备能力（VO2 max减去VeT）显著降低（年龄与储备能力的相关系数r = -0.75），这是由于VO2 max的下降幅度大于VeT。通过多元回归分析，VeT的变异性主要由VO2 max决定（占65.8%），而非年龄。随着年龄增长剧烈活动减少可能是VO2 max大幅下降的原因，而维持次最大活动可能会减弱通气阈值时VO2的下降，从而导致高于VeT水平的功能储备大幅丧失。
