Steiner Katharina Marie, Kilic Selin, Specka Michael, Scherbaum Norbert
LVR-University-Hospital Essen, Department of Psychiatry and Psychotherapy, Medical Faculty, University of Duisburg-Essen, 45147 Essen, Germany.
Center for Translational Neuro- & Behavioral Sciences (C-TNBS), University Duisburg Essen, 45147 Essen, Germany.
Brain Sci. 2025 Jun 3;15(6):599. doi: 10.3390/brainsci15060599.
BACKGROUND/OBJECTIVES: According to a diathesis-stress model for the development of mental illness, it is assumed that, in addition to pre-existing individual vulnerability, the occurrence of acute strains is an etiological factor. The SARS-CoV-2 pandemic was a collective massive stressor, which could predispose to a first manifestation of a mental disorder or the exacerbation of a pre-existing mental disorder. The aim of this study was to investigate the effects of the pandemic on the cohort of patients admitted to hospital during the first year of the pandemic.
Patients admitted to inpatient treatment in a university psychiatric hospital in an urban region from April 2020 to March 2021 were interviewed using a systematic questionnaire assessing individual stress factors in the context of the pandemic. On the basis of the interview, clinical practitioners rated the influence of the pandemic on the admission.
Six hundred and forty-five patients were interviewed. Only 6.4% showed a strong influence of the pandemic on inpatient admission. This group was characterized by a comparatively high level of socioeconomic functioning. Additionally, the majority of this group had a pre-existing mental disorder.
For the majority of patients, the pandemic had only a minor influence on their hospitalization; only for 6.4% was a high impact of the pandemic reported. We hypothesize that this group's higher socioeconomic functioning in addition to a pre-existing mental disorder made them vulnerable to pandemic-associated limitations. These data confirm a complex diathesis-stress model for the development of mental illness in the context of an acute collective stressor.
背景/目的:根据精神疾病发展的素质-应激模型,假定除了预先存在的个体易感性外,急性应激的发生也是一个病因因素。严重急性呼吸综合征冠状病毒2(SARS-CoV-2)大流行是一个集体性的巨大应激源,可能导致精神障碍的首次发作或使预先存在的精神障碍加重。本研究的目的是调查大流行对大流行第一年期间入院患者队列的影响。
对2020年4月至2021年3月期间在城市地区一家大学精神病医院接受住院治疗的患者,使用一份系统问卷进行访谈,该问卷评估了大流行背景下的个体应激因素。根据访谈,临床医生对大流行对入院的影响进行了评分。
共访谈了645名患者。只有6.4%的患者显示大流行对住院有强烈影响。该组患者的特点是社会经济功能水平相对较高。此外,该组大多数患者预先存在精神障碍。
对于大多数患者来说,大流行对他们住院的影响较小;只有6.4%的患者报告大流行有很大影响。我们推测,除了预先存在的精神障碍外,该组较高的社会经济功能使他们易受与大流行相关的限制的影响。这些数据证实了在急性集体应激源背景下精神疾病发展的复杂素质-应激模型。