Yeh Wei-Chang, Shia Wei-Chung, Hsu Yun-Ting, Huang Chun-Hui, Lee Yong-Shiuan
Department of Industrial Engineering and Engineering Management, National Tsing Hua University, Hsinchu 300, Taiwan.
Department of Industrial and Systems Engineering, Chung Yuan Christian University, Taoyuan 320, Taiwan.
Bioengineering (Basel). 2025 Jun 11;12(6):640. doi: 10.3390/bioengineering12060640.
In recent years, an increasing number of women worldwide have been affected by breast cancer. Early detection is crucial, as it is the only way to identify abnormalities at an early stage. However, most deep learning models developed for classifying breast cancer abnormalities tend to be large-scale and computationally intensive, often overlooking the constraints of cost and limited computational resources. This research addresses these challenges by utilizing the CBIS-DDSM dataset and introducing a novel concatenated classification architecture and a two-stage strategy to develop an optimized, lightweight model for breast mass abnormality classification. Through data augmentation and image preprocessing, the proposed model demonstrates a superior performance compared to standalone CNN and DNN models. The two-stage strategy involves first constructing a compact model using knowledge distillation and then refining its structure with a heuristic approach known as Simplified Swarm Optimization (SSO). The experimental results confirm that knowledge distillation significantly enhances the model's performance. Furthermore, by applying SSO's full-variable update mechanism, the final model-SSO-Concatenated NASNetMobile (SSO-CNNM)-achieves outstanding performance metrics. It attains a compression rate of 96.17%, along with accuracy, precision, recall, and AUC scores of 96.47%, 97.4%, 94.94%, and 98.23%, respectively, outperforming other existing methods.
近年来,全球越来越多的女性受到乳腺癌的影响。早期检测至关重要,因为这是在早期阶段识别异常的唯一方法。然而,大多数为乳腺癌异常分类而开发的深度学习模型往往规模庞大且计算密集,常常忽视成本和有限计算资源的限制。本研究通过利用CBIS-DDSM数据集并引入一种新颖的级联分类架构和两阶段策略,来开发一种用于乳腺肿块异常分类的优化轻量级模型,从而应对这些挑战。通过数据增强和图像预处理,所提出的模型与独立的卷积神经网络(CNN)和深度神经网络(DNN)模型相比,表现出卓越的性能。两阶段策略包括首先使用知识蒸馏构建一个紧凑模型,然后用一种称为简化群体优化(SSO)的启发式方法优化其结构。实验结果证实,知识蒸馏显著提高了模型的性能。此外,通过应用SSO的全变量更新机制,最终模型——SSO-级联NASNetMobile(SSO-CNNM)——实现了出色的性能指标。它实现了96.17%的压缩率,准确率、精确率、召回率和曲线下面积(AUC)分数分别为96.47%、97.4%、94.94%和98.23%,优于其他现有方法。