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沙维诺林A与:毒理学、药理学特征及治疗潜力

Salvinorin A and : Toxicology, Pharmacological Profile, and Therapeutic Potential.

作者信息

Calado Sara, Pires Bruno, Rosendo Luana M, Rosado Tiago, Gallardo Eugenia, Duarte Ana Paula

机构信息

Laboratório de Fármaco-Toxicologia, UBIMedical, Universidade da Beira Interior, Estrada Municipal 506, 6200-284 Covilhã, Portugal.

RISE-Health, Departamento de Ciências Médicas, Faculdade de Ciências da Saúde, Universidade da Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.

出版信息

Int J Mol Sci. 2025 Jun 11;26(12):5588. doi: 10.3390/ijms26125588.

Abstract

is a psychoactive plant presenting a complex pharmacological profile, attracting significant scientific interest due to its potential therapeutic applications and associated health risks. This review provides a comprehensive analysis of the toxic and therapeutic effects of , evaluating its potential medical applications while highlighting the risks associated with its consumption. Additionally, the review examines the plant's recreational use, global consumption trends, and legal status. By synthesising current research, this article aims to clarify the implications of use and inform future studies on its pharmacological potential and regulatory considerations.

摘要

是一种具有精神活性的植物,呈现出复杂的药理特性,因其潜在的治疗应用和相关健康风险而吸引了大量科学关注。本综述对其毒性和治疗作用进行了全面分析,评估其潜在的医学应用,同时强调与食用相关的风险。此外,该综述还考察了该植物的娱乐用途、全球消费趋势和法律地位。通过综合当前研究,本文旨在阐明其使用的影响,并为未来关于其药理潜力和监管考量的研究提供信息。

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