Hrubá Orsolya, Žigová Lucia, Hrončová Michala, Valášková Simona, Smaha Juraj, Jackuliak Peter, Kužma Martin, Mayer Alexander, Dukat Andrej, Payer Juraj, Kyselovic Jan, Gažová Andrea
Institute of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Comenius University Bratislava, 81372 Bratislava, Slovakia.
International Laser Centre, Slovak Centre of Scientific and Technical Information, 84104 Bratislava, Slovakia.
Healthcare (Basel). 2025 Jun 12;13(12):1412. doi: 10.3390/healthcare13121412.
The "weekend effect" refers to the higher risk of death for patients admitted to hospitals on weekends compared to weekdays. While this pattern is well documented in many countries, there is limited data from Central Europe, including Slovakia.
We conducted a 13-year retrospective study at a large internal medicine department in Bratislava, Slovakia, to determine (1) whether there is a weekend effect, (2) which patient groups are most affected, and (3) what clinical and demographic factors might play a role.
Using statistical tests, we analysed 45,955 hospitalisations between 2010 and 2022, comparing mortality rates between weekday (Monday-Friday) and weekend (Saturday-Sunday) admissions. We also used logistic regression to adjust for age, gender, length of stay, and re-hospitalisation. Causes of death were classified using ICD-10 codes.
Patients admitted on weekends had a significantly higher in-hospital mortality rate (15.58%, 1203 deaths among 7719 admissions) than patients admitted on weekdays (10.47%, 4002 deaths among 38,236 admissions, < 0.0001). Even after adjusting for other factors, weekend admission remained a strong predictor of death (adjusted odds ratio = 1.31, 95% CI: 1.22-1.41). Cardiovascular disease was the most common cause of death on weekends. The weekend effect persisted across all years and was particularly pronounced in the COVID-19 pandemic (2020-2021).
Our findings confirm the weekend effect in Slovakia, with patients admitted on weekends facing a higher risk of in-hospital death. Identifying the reasons behind this trend is critical to improving hospital care and ensuring consistent quality of care throughout the week.
“周末效应”指的是与工作日入院的患者相比,周末入院的患者死亡风险更高。虽然这种模式在许多国家都有充分记录,但来自中欧(包括斯洛伐克)的数据有限。
我们在斯洛伐克布拉迪斯拉发的一个大型内科部门进行了一项为期13年的回顾性研究,以确定:(1)是否存在周末效应;(2)哪些患者群体受影响最大;(3)哪些临床和人口统计学因素可能起作用。
我们使用统计检验分析了2010年至2022年间的45955例住院病例,比较了工作日(周一至周五)和周末(周六至周日)入院患者的死亡率。我们还使用逻辑回归来调整年龄、性别、住院时间和再次入院情况。使用国际疾病分类第10版(ICD - 10)编码对死亡原因进行分类。
周末入院的患者院内死亡率(15.58%,7719例入院中有1203例死亡)显著高于工作日入院的患者(10.47%,38236例入院中有4002例死亡,P < 0.0001)。即使在调整其他因素后,周末入院仍然是死亡的有力预测因素(调整后的优势比 = 1.31,95%置信区间:1.22 - 1.41)。心血管疾病是周末最常见的死亡原因。周末效应在所有年份都持续存在,在2019 - 2021年的新冠疫情期间尤为明显。
我们的研究结果证实了斯洛伐克存在周末效应,周末入院的患者面临更高的院内死亡风险。找出这一趋势背后的原因对于改善医院护理以及确保一周内护理质量的一致性至关重要。