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医院在周末收治病人时的死亡率是否更高?一项观察性研究分析了加泰罗尼亚地区医院急诊收治周末入院患者的“周末效应”。

Do hospitals have a higher mortality rate on weekend admissions? An observational study to analyse weekend effect on urgent admissions to hospitals in Catalonia.

机构信息

IMIM, Barcelona, Spain.

Agència de Qualitat i Avaluació Sanitàries de Catalunya, Barcelona, Spain.

出版信息

BMJ Open. 2021 Nov 29;11(11):e047836. doi: 10.1136/bmjopen-2020-047836.

Abstract

BACKGROUND

'Weekend effect' is a term used to describe the increased mortality associated with weekend emergency admissions to hospital, in contrast with admission on weekdays. The objective of the present study is to determine whether the weekend effect is present in hospitals in Catalonia.

METHODS

We analysed all urgent admissions in Catalonia in 2018, for a group of pathologies. Two groups were defined (those admitted on a weekday and those admitted on a weekend). We obtained mortality at 3, 7, 15 and 30 days, and applied a proportions test to both groups. Additionally, we used Cox's regression for mortality at 30 days, using the admission on a weekend as the exposition, adjusting by socioeconomic and clinical variables. We used the hospital discharge database and the Central Registry of the Insured Population.

RESULTS

72 427 admissions for the selected pathologies during 2018 were found. No statistically significant differences in mortality at 30 days (p=0.524) or at 15 days (p=0.119) according to the day of admission were observed. However, significant differences were found in mortality at 7 days (p=0.025) and at 3 days (p=0.002). The hazard rate associated with the weekend was 1.13 (95% CI: 1.04 to 1.23). By contrast, the adjusted HR of the weekend interaction with time was 0.99 (95% CI: 0.99 to 1.00).

CONCLUSIONS

There is a weekend effect, but it is not constant in time. This could suggest the existence of dysfunctions in the quality of care during the weekend.

摘要

背景

“周末效应”是一个术语,用于描述与周末紧急住院相关的死亡率增加,与工作日住院相比。本研究的目的是确定“周末效应”是否存在于加泰罗尼亚的医院中。

方法

我们分析了 2018 年加泰罗尼亚所有的紧急入院病例,针对一组特定的病症。定义了两个组(在工作日入院的和在周末入院的)。我们获得了 3、7、15 和 30 天的死亡率,并对两组进行了比例检验。此外,我们使用 Cox 回归分析了 30 天的死亡率,将周末入院作为暴露因素,并调整了社会经济和临床变量。我们使用了医院出院数据库和参保人口中央登记处。

结果

2018 年发现了 72427 例选定病症的入院病例。根据入院日期,30 天(p=0.524)或 15 天(p=0.119)的死亡率没有统计学上的显著差异。然而,在 7 天(p=0.025)和 3 天(p=0.002)的死亡率上观察到了显著差异。周末与死亡率相关的危险率为 1.13(95%CI:1.04 至 1.23)。相比之下,周末与时间的调整后的 HR 交互作用为 0.99(95%CI:0.99 至 1.00)。

结论

存在“周末效应”,但它不是一成不变的。这可能表明周末期间医疗质量存在功能障碍。

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