探究身体成分分析对成年男性慢性阻塞性肺疾病患者生活质量及焦虑抑郁的影响。
Investigating the Impact of Body Composition Analysis on Quality of Life and Anxiety-Depression in Adult Males with Chronic Obstructive Pulmonary Disease.
作者信息
Kurtoğlu Ahmet, Eken Özgür, Çiftçi Rukiye, Balıkçı Çiçek İpek, Durmaz Dilber, Argalı Deniz Mine, Aldhahi Monira I
机构信息
Department of Coaching Education, Sport Science Faculty, Bandırma Onyedi Eylul University, Balıkesir 10250, Turkey.
Department of Physical Education and Sport Teaching, Sport Science Faculty, Inonu University, Malatya 44280, Turkey.
出版信息
Healthcare (Basel). 2025 Jun 16;13(12):1442. doi: 10.3390/healthcare13121442.
BACKGROUND/OBJECTIVES: Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder characterized by systemic manifestations, including altered body composition, reduced quality of life, and psychological distress. Despite its significance, the relationship between body composition parameters and symptoms of fatigue, anxiety, and depression in patients with COPD remains underexplored. This study aimed to examine the association between detailed body composition metrics and quality of life, fatigue, and anxiety and depression symptoms in male patients with COPD compared to healthy controls.
METHODS
This cross-sectional study included 49 men with COPD and 51 age-matched healthy controls aged 50-80 years. Body composition was assessed using bioelectrical impedance analysis (BIA). Pulmonary function, dyspnea, activities of daily living, and psychological status were evaluated using spirometry, the Medical Research Council Dyspnea Scale, the London Chest Activity of Daily Living Scale (LCADL), and the Hospital Anxiety and Depression Scale (HADS), respectively.
RESULTS
Compared to the controls, patients with COPD exhibited significantly lower forced expiratory volume in one second (FEV: 1.1 vs. 2.16 L; < 0.001), lower fat mass (15.0 vs. 24.3 kg; < 0.001), and higher muscle mass (53.8 vs. 42.0 kg; < 0.001). They also reported significantly greater fatigue (Borg scale: 4 vs. 0; < 0.001), higher anxiety (8 vs. 5; = 0.006), and depression scores (11 vs. 5; < 0.001), along with more pronounced limitations in their daily activities.
CONCLUSIONS
COPD is associated with profound impairments in body composition, physical function, and mental health. Detailed body composition analysis using BIA provides valuable clinical insights and may aid in tailoring individualized interventions to improve quality of life and psychological outcomes in COPD management.
背景/目的：慢性阻塞性肺疾病（COPD）是一种进行性呼吸系统疾病，其特征为全身表现，包括身体成分改变、生活质量下降和心理困扰。尽管其具有重要意义，但COPD患者身体成分参数与疲劳、焦虑和抑郁症状之间的关系仍未得到充分研究。本研究旨在探讨与健康对照相比，COPD男性患者详细身体成分指标与生活质量、疲劳以及焦虑和抑郁症状之间的关联。
方法
这项横断面研究纳入了49名年龄在50至80岁之间的COPD男性患者和51名年龄匹配的健康对照。使用生物电阻抗分析（BIA）评估身体成分。分别使用肺活量测定法、医学研究委员会呼吸困难量表、伦敦胸部日常生活活动量表（LCADL）和医院焦虑抑郁量表（HADS）评估肺功能、呼吸困难、日常生活活动和心理状态。
结果
与对照组相比，COPD患者一秒用力呼气量显著降低（FEV1：1.1 vs. 2.16 L；P<0.001），脂肪量更低（15.0 vs. 24.3 kg；P<0.001），肌肉量更高（53.8 vs. 42.0 kg；P<0.001）。他们还报告有明显更严重 的疲劳（Borg量表：4 vs. 0；P<0.001）、更高的焦虑（8 vs. 5；P = 0.
Zotero 插件