Liu Ying, Liu Wenjing, Huang Haozhe, Zhang Caixia, Yang Long
College of Plant Protection, Shandong Agricultural University, Taian 271018, China.
College of Agronomy, Shandong Agricultural University, Taian 271018, China.
Genes (Basel). 2025 May 30;16(6):680. doi: 10.3390/genes16060680.
The NBS-LRR gene family plays a critical role in plant disease resistance and is considered a key determinant of plant immune responses. Research on the NBS-LRR gene family has grown rapidly, with significant progress driven by advances of molecular biology techniques. However, to date, there has been no systematic identification of NBS-LRR genes in species. : In this study, we systematically characterized the NBS gene families in three genomes, investigated the evolution and environmental selection during the species formation, and explored the key NBS genes involved in disease resistance. : Results showed that 1226 NBS genes are present across the three genomes, and 76.62% of the members in could be traced back to their parental genomes. In addition, whole-genome duplication was found to contribute significantly to the expansion of NBS gene families. In addition, many NBS genes associated with disease resistance were identified, including one multi-disease resistance gene. : This study provides new insights into the formation of NBS gene families in and offers new clues for understanding plant immunity.
NBS-LRR基因家族在植物抗病性中起着关键作用，被认为是植物免疫反应的关键决定因素。对NBS-LRR基因家族的研究发展迅速，分子生物学技术的进步推动了该领域取得重大进展。然而，迄今为止，尚未对某物种中的NBS-LRR基因进行系统鉴定。在本研究中，我们系统地鉴定了三个某基因组中的NBS基因家族，研究了物种形成过程中的进化和环境选择，并探索了参与抗病性的关键NBS基因。结果表明，三个某基因组中共有1226个NBS基因，某中76.62%的成员可追溯到其亲本基因组。此外，发现全基因组复制对NBS基因家族的扩张有显著贡献。此外，还鉴定出许多与抗病性相关的NBS基因，包括一个多抗病基因。本研究为某中NBS基因家族的形成提供了新见解，并为理解植物免疫提供了新线索。
