Alnasser Saeed Mufleh, Babakair Reem Abdullah, Al Mukhlid Amal Fahad, Al Hassan Salihah Saleh Saeed, Nuhmani Shibili, Muaidi Qassim
Alyvia Rehabilitation Center, Abha Private International Hospital, Abha 1794, Saudi Arabia.
Department of Physical Therapy, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam 31451, Saudi Arabia.
J Clin Med. 2025 Jun 10;14(12):4109. doi: 10.3390/jcm14124109.
This systematic review and meta-analysis aims to provide a detailed analysis of the current state of knowledge on Progressive Exercise Training (PET), encompassing its diverse modalities, effects on bone mineral density (BMD), quality of life outcomes, and implications for clinical practice. A structured search strategy was employed to retrieve literature from seven databases (PubMed, Web of Science, Scopus, MEDLINE, Science Direct, EBSCO, CINHAL, and PEDro) yielded twenty-four randomized controlled trials (RCTs) meeting the inclusion criteria. The methodological quality of studies was evaluated using the PEDro scale. Meta-analyses were carried out to comprehensively assess the collective impact of PET on bone mineral density outcomes. PET exhibited favorable effects on BMD across multiple anatomical sites, encompassing the femoral neck, total hip, lumbar spine, and others. This effect was observed across different age groups and genders, highlighting its potential benefits for diverse populations. PET encompasses a range of modalities, including resistance training, aerobic training, impact training, whole-body vibration, and tai chi, with a duration ranging from 4 to 24 months, with weekly sessions varying from two to five times. Some studies combined these modalities, reflecting the adaptability of PET to individual preferences and capabilities. Tailoring exercise prescriptions to individual needs emerged as a feasible approach within PET. A subset of studies assessed quality of life using validated instruments such as the 36-item short form survey (SF-36), shortened osteoporosis quality of life questionnaire (SOQLQ), and menopause quality of life instrument (MENQOL). This study provides strong evidence that PET represents a promising intervention for osteoporosis management, enhancing BMD and, to some extent, quality of life. PET offers a beacon of hope for better skeletal health and well-being in individuals grappling with osteoporosis, emphasizing the need for its incorporation into clinical practice.
本系统评价和荟萃分析旨在详细分析渐进性运动训练（PET）的现有知识状况，包括其不同形式、对骨密度（BMD）的影响、生活质量结果以及对临床实践的意义。采用结构化检索策略从七个数据库（PubMed、科学网、Scopus、MEDLINE、科学Direct、EBSCO、CINHAL和PEDro）中检索文献，共获得24项符合纳入标准的随机对照试验（RCT）。使用PEDro量表评估研究的方法学质量。进行荟萃分析以全面评估PET对骨密度结果的总体影响。PET对多个解剖部位的骨密度均有有益影响，包括股骨颈、全髋、腰椎等。在不同年龄组和性别中均观察到这种效果，凸显了其对不同人群的潜在益处。PET包括一系列形式，如阻力训练、有氧训练、冲击训练、全身振动和太极拳，持续时间为4至24个月，每周训练次数从两次到五次不等。一些研究将这些形式结合起来，反映了PET对个人偏好和能力的适应性。根据个人需求定制运动处方是PET中的一种可行方法。一部分研究使用经过验证的工具评估生活质量，如36项简短调查问卷（SF-36）、缩短版骨质疏松症生活质量问卷（SOQLQ）和更年期生活质量工具（MENQOL）。本研究提供了有力证据，表明PET是骨质疏松症管理的一种有前景的干预措施，可提高骨密度，并在一定程度上改善生活质量。PET为患有骨质疏松症的个体改善骨骼健康和幸福感带来了希望之光，强调了将其纳入临床实践的必要性。
