Pálok Diána, Kiss Barbara, Élő László Gergely, Dósa Ágnes, Zubek László, Élő Gábor
Doctoral College, Semmelweis University, Üllői Street 26, H-1085 Budapest, Hungary.
Department of Anesthesiology and Intensive Therapy, Semmelweis University, Üllői Street 78, H-1082 Budapest, Hungary.
J Clin Med. 2025 Jun 11;14(12):4145. doi: 10.3390/jcm14124145.
Professional knowledge and experience of healthcare organization went through continuous change and development with the progression of COVID-19 pandemic waves. However, carefully developed guidelines for cardiopulmonary resuscitation (CPR) remained largely unchanged regardless of the epidemic situation, with the largest change being a more prominent bioethical approach. It would be possible to further improve the quality of CPR by systematic data collection, the facilitation of prospective studies, and further development of the methodology based on this evidence, as well as by providing information and developing provisions on interventions with expected poor outcomes, and ultimately by refusing resuscitation. : This study involved the critical collection and analysis of literary data originating from the Web of Science and PubMed databases concerning bioethical aspects and the efficacy of CPR during the COVID-19 pandemic. : According to the current professional recommendation of the European Resuscitation Council (ERC), CPR should be initiated immediately in case of cardiac arrest in the absence of an exclusionary circumstance. One such circumstance is explicit refusal of CPR by a well-informed patient, which in practice takes the form of a prior declaration. ERC prescribes the following conjunctive conditions for do-not-attempt CPR (DNACPR) declarations: present, real, and applicable. It is recommended to take the declaration as a part of complex end-of-life planning, with the corresponding documentation available in an electronic database. The pandemic has brought significant changes in resuscitation practice at both lay and professional levels as well. Incidence of out-of-hospital resuscitation (OHCA) did not differ compared to the previous period, while cardiac deaths in public places almost halved during the epidemic ( < 0.001) as did the use of AEDs ( = 0.037). The number of resuscitations performed by bystanders and by the emergency medical service (EMS) also showed a significant decrease ( = 0.001), and the most important interventions (defibrillation, first adrenaline time) suffered a significant delay. Secondary survival until hospital discharge thus decreased by 50% during the pandemic period. : The COVID-19 pandemic provided a significant impetus to the revision of guidelines. While detailed methodology has changed only slightly compared to the previous procedures, the DNACPR declaration regarding self-determination is mentioned in the context of complex end-of-life planning. The issue of safe environment has come to the fore for both lay and trained resuscitators. Prospective evaluation of standardized methods can further improve the patient's autonomy and quality of life. Since clinical data are controversial, further prospective controlled studies are needed to evaluate the real hazards of aerosol-generating procedures.
随着新冠疫情浪潮的推进,医疗机构的专业知识和经验经历了持续的变化与发展。然而,精心制定的心肺复苏(CPR)指南在很大程度上保持不变,无论疫情形势如何,最大的变化是一种更为突出的生物伦理方法。通过系统的数据收集、促进前瞻性研究以及基于此证据进一步发展方法,以及提供关于预期效果不佳的干预措施的信息并制定相关规定,最终通过拒绝复苏,有可能进一步提高心肺复苏的质量。:本研究涉及对来自科学网和PubMed数据库的关于新冠疫情期间生物伦理方面和心肺复苏效果的文献数据进行批判性收集和分析。:根据欧洲复苏委员会(ERC)目前的专业建议,在不存在排除情况的心脏骤停病例中应立即开始心肺复苏。一种这样的情况是,明智的患者明确拒绝心肺复苏,在实践中这采取预先声明的形式。ERC规定了不尝试心肺复苏(DNACPR)声明的以下联合条件:存在、真实且适用。建议将该声明作为复杂的临终规划的一部分,并在电子数据库中提供相应的文件。疫情在非专业和专业层面的复苏实践中也带来了重大变化。院外复苏(OHCA)的发生率与前一时期相比没有差异,而疫情期间公共场所的心脏死亡人数几乎减半(<0.001),自动体外除颤器(AED)的使用情况也是如此(=0.037)。旁观者和紧急医疗服务(EMS)进行的复苏次数也显著减少(=0.001),最重要的干预措施(除颤、首次使用肾上腺素时间)出现了显著延迟。因此,疫情期间直至出院的二次生存率下降了50%。:新冠疫情为指南的修订提供了重要动力。虽然详细方法与以前的程序相比仅略有变化,但在复杂的临终规划背景下提到了关于自主决定权的DNACPR声明。安全环境问题对于非专业和受过训练的复苏人员都已变得突出。对标准化方法的前瞻性评估可以进一步提高患者的自主权和生活质量。由于临床数据存在争议,需要进一步进行前瞻性对照研究来评估产生气溶胶程序的实际风险。