Fidelsberger Luise, Fischer Claudia, Kreye Gudrun, Meran Eleonora, Likar Rudolf, van Tulder Raphael, Stettner Haro, Masel Eva Katharina, Singer Josef, Le Nguyen-Son
Division of Palliative Care, Division of Internal Medicine 2, University Hospital Krems, 3500 Krems, Austria.
Karl Landsteiner University of Health Sciences, 3500 Krems, Austria.
J Clin Med. 2025 Jun 13;14(12):4206. doi: 10.3390/jcm14124206.
Early integration of palliative care (PC) improves outcomes for patients with life-limiting diseases (LLDs). This study evaluated the effectiveness of the Palliative Care and Rapid Emergency Screening (P-CaRES) tool-originally developed for emergency settings-in identifying unmet PC needs among patients admitted to internal medicine wards. In this retrospective study, the P-CaRES tool was applied to medical records of patients with LLDs. Demographic and clinical data were extracted from charts. Logistic regression identified predictors of PC receipt; survival was analyzed using Kaplan-Meier estimates and log-rank tests. Among 2509 patients screened, 631 (23.9%) had at least one LLD. Of these, 451 (71.5%) were identified as having PC needs. However, only 132 (20.9%) received PC services-126 with documented need and 6 without. Advanced cancer (OR = 6.46, < 0.001), a positive response to the surprise question (OR = 4.88, = 0.008), and frequent hospitalizations (OR = 2.24, < 0.001) predicted PC receipt. Median survival declined with increasing disease burden (10 vs. 372 days for patients with ≥3 vs. 1 LLD), unmet PC needs (85 vs. 1383 days), and a "yes" response to the surprise question (79 vs. 1598 days) (all < 0.001). The P-CaRES tool effectively identified PC needs in patients with LLDs, including those with cancer. Clinical indicators such as frequent hospital admissions, a positive response to the surprise question, and multimorbidity predicted both the need for PC and shorter survival. Nonetheless, substantial gaps existed between identified needs and PC delivery-especially for non-cancer patients. Structured screening and timely referrals may bridge this gap and improve care for seriously ill individuals.
早期整合姑息治疗(PC)可改善患有生命有限疾病(LLD)患者的预后。本研究评估了最初为急诊环境开发的姑息治疗与快速急诊筛查(P-CaRES)工具在识别内科病房住院患者未满足的PC需求方面的有效性。在这项回顾性研究中,P-CaRES工具被应用于LLD患者的病历。从病历中提取人口统计学和临床数据。逻辑回归确定了接受PC治疗的预测因素;使用Kaplan-Meier估计和对数秩检验分析生存率。在筛查的2509例患者中,631例(23.9%)患有至少一种LLD。其中,451例(71.5%)被确定有PC需求。然而,只有132例(20.9%)接受了PC服务——126例有记录需求,6例无记录需求。晚期癌症(比值比[OR]=6.46,P<0.001)、对意外问题的肯定回答(OR=4.88,P=0.008)和频繁住院(OR=2.24,P<0.001)预测了PC治疗的接受情况。随着疾病负担增加(≥3种与1种LLD的患者分别为10天和372天)、未满足的PC需求(85天和1383天)以及对意外问题的“是”回答(79天和1598天),中位生存期下降(均P<0.001)。P-CaRES工具有效地识别了LLD患者,包括癌症患者的PC需求。频繁住院、对意外问题的肯定回答和多种疾病等临床指标预测了对PC的需求和较短的生存期。尽管如此,已识别的需求与PC服务提供之间仍存在很大差距——尤其是对于非癌症患者。结构化筛查和及时转诊可能弥合这一差距,并改善对重症患者的护理。