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手术后通气婴儿气管内吸痰期间的脑近红外光谱和心阻抗血流图:一项可行性研究

Cerebral Near-Infrared Spectroscopy and Electrical Cardiometry During Endotracheal Suction in Ventilated Infants Following Surgery: A Feasibility Study.

作者信息

Nissen Matthias, Tröbs Ralf-Bodo

机构信息

Department of Pediatric Surgery, Marien Hospital Witten, St. Elisabeth Gruppe, Ruhr-University of Bochum, Marienplatz, D-58452 Witten, Germany.

Department of General-, Visceral-, and Pediatric Surgery, Section of Pediatric Surgery and Urology, St. Vinzenz Hospital, Academic Teaching Hospital of Georg-August-University Göttingen, Am Busdorf, D-33908 Paderborn, Germany.

出版信息

Life (Basel). 2025 May 31;15(6):901. doi: 10.3390/life15060901.

Abstract

UNLABELLED

Near-Infrared Spectroscopy (NIRS) and Electrical Cardiometry (EC) are promising non-invasive techniques for monitoring tissue oxygenation and hemodynamics, particularly in surgically ill infants who struggle to maintain cerebral oxygenation and systemic perfusion. There is limited data regarding the combined use of these techniques during respiratory procedures such as endotracheal suction in intubated infants.

METHODS

The effects of 38 endotracheal suction maneuvers on cerebral oxygenation and cardiovascular hemodynamics were investigated in seven intubated infants following non-cardiac surgery. Parameters such as cerebral oxygenation and EC-derived metrics including heart rate, stroke volume, and cardiac output were assessed.

RESULTS

Gestational and postnatal age were 31 weeks and 16 days. During endotracheal suction, the heart rate decreased but returned to baseline afterward. After the procedure, the cerebral oxygenation, stroke volume, and cardiac output increased.

CONCLUSIONS

Cerebral and systemic hemodynamics were altered during endotracheal suction maneuvers in ventilated infants. Combining NIRS and EC for monitoring cardiovascular and cerebrovascular physiology may enable more individualized therapy, helping to minimize cerebral injury in this vulnerable population.

摘要

未标注

近红外光谱法(NIRS)和心电阻抗法(EC)是用于监测组织氧合和血流动力学的有前景的非侵入性技术,尤其适用于难以维持脑氧合和全身灌注的外科手术患儿。关于这些技术在呼吸操作(如对插管婴儿进行气管内吸引)期间联合使用的数据有限。

方法

在7名非心脏手术后插管的婴儿中,研究了38次气管内吸引操作对脑氧合和心血管血流动力学的影响。评估了诸如脑氧合和源自EC的指标,包括心率、每搏输出量和心输出量等参数。

结果

胎龄和出生后年龄分别为31周和16天。在气管内吸引期间,心率下降,但随后恢复到基线水平。操作后,脑氧合、每搏输出量和心输出量增加。

结论

通气婴儿在气管内吸引操作期间脑和全身血流动力学发生改变。联合使用NIRS和EC监测心血管和脑血管生理状况可能实现更个体化的治疗,有助于将这一脆弱人群的脑损伤降至最低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69e7/12193928/03b8630a3114/life-15-00901-g001.jpg

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