Romualdi Giovanni, Buzzi Matilde, Ruggeri Pier Giuseppe, Tommasi Federico, Giorgetti Alessio, Cavalieri Stefano, Mencucci Rita
Eye Clinic, Department of Neuroscience, Psychology, Pharmacology and Child Health (NEUROFARBA), University of Florence, Largo Brambilla 3, 50134 Florence, Italy.
Department of Physics and Astronomy, University of Florence, via Giovanni Sansone 1, 50019 Sesto Fiorentino, Italy.
Life (Basel). 2025 Jun 19;15(6):984. doi: 10.3390/life15060984.
A novel enhanced monofocal intraocular lens (IOL) has been developed to improve functional intermediate vision, maintaining a distance vision comparable to a standard monofocal lens and avoiding the drawbacks of multifocal IOLs. The aim of this study is to perform optical bench analysis and to evaluate refractive and visual outcomes and patient satisfaction. : This prospective comparative single-center study was conducted in Careggi Hospital, University of Florence (Italy). We included 100 eyes from 50 patients who underwent bilateral cataract surgery. One group received the standard monofocal Tecnis GCB00 IOL, while the other group received the novel enhanced monofocal Evolux IOL. We evaluated binocular visual and refractive outcomes at 6 months after surgery. Binocular defocus curves and contrast sensitivity (CS) were also assessed. Optical quality was also analyzed in terms of higher-order aberrations (HOAs), modulation transfer function (MTF), objective scatter index (OSI), Strehl ratio, effective lens position (ELP), and halo analysis. A Patient-Reported Spectacle Independence Questionnaire (PRSIQ) was performed to assess spectacle independence outcomes. Finally, we analyzed the optical bench of both lenses. : All eyes implanted with Evolux achieved excellent distance vision, comparable to that achieved with GCB00. Evolux showed better intermediate and near vision, without any loss of visual quality, contrast sensitivity, or the presence of halos and photic phenomena. The optical bench analysis confirmed the different optical properties of the two lenses and supported the behavior obtained with the clinical defocus curve. : These preliminary results show good refractive accuracy and visual outcomes for the enhanced monofocal IOL Evolux after cataract surgery. Further studies are needed to confirm our findings in terms of the number of patients and the period of follow-up.
一种新型增强型单焦点人工晶状体（IOL）已被研发出来，以改善功能性中距离视力，保持与标准单焦点晶状体相当的远视力，并避免多焦点IOL的缺点。本研究的目的是进行光学平台分析，评估屈光和视觉结果以及患者满意度。：这项前瞻性比较单中心研究在意大利佛罗伦萨大学卡雷吉医院进行。我们纳入了50例接受双侧白内障手术患者的100只眼睛。一组接受标准单焦点Tecnis GCB00 IOL，而另一组接受新型增强型单焦点Evolux IOL。我们在术后6个月评估双眼视觉和屈光结果。还评估了双眼散焦曲线和对比敏感度（CS）。还从高阶像差（HOA）、调制传递函数（MTF）、客观散射指数（OSI）、斯特列尔比率、有效晶状体位置（ELP）和光晕分析方面分析了光学质量。进行了患者报告的眼镜独立性问卷（PRSIQ）以评估眼镜独立性结果。最后，我们分析了两种晶状体的光学平台。：所有植入Evolux的眼睛都获得了出色的远视力，与GCB00所达到的相当。Evolux显示出更好的中距离和近视力，且视觉质量、对比敏感度没有任何损失，也没有光晕和光现象。光学平台分析证实了两种晶状体不同的光学特性，并支持了临床散焦曲线所获得的表现。：这些初步结果表明，白内障手术后增强型单焦点IOL Evolux具有良好的屈光准确性和视觉结果。需要进一步的研究来在患者数量和随访时间方面证实我们的发现。
