经颅颞叶干扰刺激（tTIS）期间低频伪影的特征分析。
Characterizing low-frequency artifacts during transcranial temporal interference stimulation (tTIS).
作者信息
von Conta Jill, Kasten Florian H, Ćurčić-Blake Branislava, Schellhorn Klaus, Herrmann Christoph S
机构信息
Experimental Psychology Lab, Department of Psychology, European Medical School, Cluster of Excellence "Hearing4All", Carl von Ossietzky University, Oldenburg, Germany.
Neuroimaging Unit, European Medical School, Carl von Ossietzky University, Oldenburg, Germany.
出版信息
Neuroimage Rep. 2022 Jun 21;2(3):100113. doi: 10.1016/j.ynirp.2022.100113. eCollection 2022 Sep.
Transcranial alternating current stimulation (tACS) is a well-established brain stimulation technique to modulate human brain oscillations. However, due to the strong electro-magnetic artifacts induced by the stimulation current, the simultaneous measurement of tACS effects during neurophysiological recordings in humans is challenging. Recently, transcranial temporal interference stimulation (tTIS) has been introduced to stimulate neurons at depth non-invasively. During tTIS, two high-frequency sine waves are applied, that interfere inside the brain, resulting in amplitude modulated waveforms at the target frequency. Given appropriate hardware, we show that neurophysiological data during tTIS may be acquired without stimulation artifacts at low-frequencies. However, data must be inspected carefully for possible low-frequency artifacts. Our results may help to design experimental setups to record brain activity during tTIS, which may foster our understanding of its underlying mechanisms.
经颅交流电刺激（tACS）是一种成熟的脑刺激技术，用于调节人类脑振荡。然而，由于刺激电流会产生强烈的电磁伪迹，在人类神经生理学记录过程中同时测量tACS效应具有挑战性。最近，经颅颞干扰刺激（tTIS）已被引入，用于非侵入性地刺激深部神经元。在tTIS期间，会施加两个高频正弦波，它们在脑内相互干扰，从而在目标频率处产生调幅波形。在具备适当硬件的情况下，我们表明在tTIS期间可以采集到无低频刺激伪迹的神经生理学数据。然而，必须仔细检查数据是否存在可能的低频伪迹。我们的结果可能有助于设计实验装置以记录tTIS期间的脑活动，这可能增进我们对其潜在机制的理解。
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