Zou Yan, Huang Li-Chun, Zhao Dong, He Meng-Jie, Han Dan, Su Danting, Xu Peiwei, Zhang Ronghua
Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Front Public Health. 2025 Jun 11;13:1553077. doi: 10.3389/fpubh.2025.1553077. eCollection 2025.
To assess the nutritional status of vitamin D and to analyze the influencing factors of vitamin D deficiency among children and adolescents.
Data from 1,827 children and adolescents aged 6-17 years from the nutrition and health surveillance of Zhejiang province, China, were analyzed. The serum concentration of 25-(OH)D were measured using High-Performance Liquid Chromatography-Tandem Mass Spectrometry. The prevalence of vitamin D deficiency and insufficiency were calculated. Ordinal regression were used to identify the influencing factors of vitamin D deficiency and insufficiency.
The mean 25-(OH)D concentration was 20.84 ± 6.34 μg/L. Among the participants, 37.4% had vitamin D insufficiency (25-(OH)D <20 μg/L) and 7.8% had vitamin D deficiency (25-(OH)D <12 μg/L). Age group (Wald = 5.921, = 0.015), sex (Wald = 6.206, = 0.013), overweight/obesity (Wald = 3.894, = 0.048), and outdoor activity time (Wald = 4.113, = 0.043) were the influencing factors of children and adolescents with insufficiency/deficiency vitamin D status.
Our study assessed the nutritional status of vitamin D and analyzed the influencing factors of vitamin D deficiency among children and adolescents in the eastern coastal areas of China. The results indicated a significant prevalence of vitamin D insufficiency and deficiency. Key influencing factors included age group, sex, overweight/obesity, and outdoor activity time. These findings highlight the need for targeted interventions to improve vitamin D levels in children and adolescents. Specifically, promoting adequate outdoor activity and addressing overweight/obesity could be effective strategies to enhance vitamin D status in this population.
评估儿童和青少年维生素D的营养状况，并分析维生素D缺乏的影响因素。
分析了来自中国浙江省营养与健康监测的1827名6至17岁儿童和青少年的数据。采用高效液相色谱-串联质谱法测定血清25-(OH)D浓度。计算维生素D缺乏和不足的患病率。采用有序回归分析确定维生素D缺乏和不足的影响因素。
25-(OH)D平均浓度为20.84±6.34μg/L。参与者中，37.4%维生素D不足（25-(OH)D<20μg/L），7.8%维生素D缺乏（25-(OH)D<12μg/L）。年龄组（Wald=5.921，P=0.015）、性别（Wald=6.206，P=0.013）、超重/肥胖（Wald=3.894，P=0.048）和户外活动时间（Wald=4.113，P=0.043）是维生素D不足/缺乏状态儿童和青少年的影响因素。
本研究评估了中国东部沿海地区儿童和青少年维生素D的营养状况，并分析了维生素D缺乏的影响因素。结果表明维生素D不足和缺乏的患病率较高。主要影响因素包括年龄组、性别、超重/肥胖和户外活动时间。这些发现凸显了采取针对性干预措施以提高儿童和青少年维生素D水平的必要性。具体而言，促进充足的户外活动和解决超重/肥胖问题可能是提高该人群维生素D状况的有效策略。
