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对有减肥手术史患者的妊娠结局评估。

Evaluation of pregnancy outcomes in patients with a history of bariatric surgery.

作者信息

Atlihan Ufuk, Yavuz Onur, Ata Can, Avsar Huseyin Aytug, Erkilinc Selcuk

机构信息

Department of Obstetrics and Gynecology, Merkezefendi Hospital, Manisa, Türkiye.

Department of Obstetrics and Gynecology, Dokuz Eylul University School of Medicine, Izmir, Türkiye.

出版信息

Front Med (Lausanne). 2025 Jun 11;12:1609344. doi: 10.3389/fmed.2025.1609344. eCollection 2025.

Abstract

INTRODUCTION

Obesity and overweight are significant risk factors for perinatal morbidity and mortality, and an increasing number of women of reproductive age are being offered bariatric surgery. The present study investigated the outcomes of pregnancies and births after bariatric surgery (BS).

MATERIALS AND METHODS

All patients who gave birth at our clinic between 2018 and 2023 were included in the study. Individuals who had undergone BS previously were identified using the hospital database, and their medical birth records were obtained for data on pregnancy, delivery, and perinatal results. The results of women who had undergone BS previously were analyzed by comparing them with other pregnancies.

RESULTS

A total of 298 women who had undergone BS previously and 4,374 women who had not undergone surgeries were included in the study. The BS group had higher rates of abortion ( = 0.009) and IVF history ( < 0.001). Additionally, the incidence of pregnancy-induced hypertension ( < 0.001), preeclampsia ( = 0.04), gestational diabetes (GDM) ( < 0.001), premature birth ( < 0.001), cesarean delivery ( < 0.001), and small for gestational age ( < 0.001) was significantly higher in the BS group.

CONCLUSION

Given the potential hazards associated with obesity in women of reproductive age, BS may be seen as a prudent course of therapy. Our study concluded that pregnancy prognosis is closely correlated with BMI at the time of pregnancy. Previous research revealed similar findings between groups in terms of pregnancy prognosis and pregnancy complications in obese and extremely obese patient groups.

摘要

引言

肥胖和超重是围产期发病和死亡的重要危险因素,越来越多的育龄妇女接受了减肥手术。本研究调查了减肥手术后的妊娠和分娩结局。

材料与方法

本研究纳入了2018年至2023年在我们诊所分娩的所有患者。通过医院数据库识别先前接受过减肥手术的个体,并获取他们的医疗分娩记录以获取有关妊娠、分娩和围产期结果的数据。通过将先前接受过减肥手术的女性的结果与其他妊娠进行比较来分析。

结果

本研究共纳入298名先前接受过减肥手术的女性和4374名未接受过手术的女性。减肥手术组的流产率(=0.009)和体外受精史发生率(<0.001)更高。此外,减肥手术组妊娠高血压(<0.001)、先兆子痫(=0.04)、妊娠期糖尿病(GDM)(<0.001)、早产(<0.001)、剖宫产(<0.001)和小于胎龄儿(<0.001)的发生率显著更高。

结论

鉴于育龄女性肥胖存在潜在危害,减肥手术可能被视为一种谨慎的治疗方法。我们的研究得出结论,妊娠预后与妊娠时的BMI密切相关。先前的研究在肥胖和极度肥胖患者组的妊娠预后和妊娠并发症方面显示了组间相似的结果。

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