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细菌感染还是病毒感染:一例年轻免疫功能正常成年人的中枢神经系统感染病例

Bacterial or Viral: A Case of Central Nervous System Infection in a Young, Immunocompetent Adult.

作者信息

Hamieh Amal, Elias Richard, Selim Heba, Elias Joseph

机构信息

Internal Medicine, Al Fujairah Hospital, Emirates Health Services, Al Fujairah, ARE.

Neurology, Zagazig University, Zagazig, EGY.

出版信息

Cureus. 2025 May 25;17(5):e84801. doi: 10.7759/cureus.84801. eCollection 2025 May.

Abstract

Herpes simplex virus (HSV) is a well-documented cause of encephalitis. However, its occurrence alongside concurrent bacterial infections is less commonly reported. Hence, we present this case report, which aims to trace the etiology of acute encephalitis in our patient, a 22-year-old farm attendant, who initially received intravenous and oral antibiotics that may have distorted the lumbar puncture results. The onset of his illness included typical symptoms such as fever, seizures, and altered mental status. The possibility of bacterial co-infection with HSV-1 viral meningoencephalitis, combined with the early administration of antibiotics in our patient, has inspired this case report to highlight the differential diagnosis concerning the microbiological epidemiology of meningoencephalitis, including concurrent bacterial, viral, and fungal infections.

摘要

单纯疱疹病毒(HSV)是一种有充分文献记载的脑炎病因。然而,其与同时发生的细菌感染并存的情况较少被报道。因此,我们呈现此病例报告,旨在追踪我们这位患者(一名22岁的农场工人)急性脑炎的病因,该患者最初接受了静脉和口服抗生素治疗,这可能扭曲了腰椎穿刺结果。他发病时出现了发热、癫痫发作和精神状态改变等典型症状。该患者细菌与HSV - 1病毒性脑膜脑炎合并感染的可能性,以及早期使用抗生素的情况,促使本病例报告强调了关于脑膜脑炎微生物流行病学的鉴别诊断,包括同时发生的细菌、病毒和真菌感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c748/12187976/84ca047371eb/cureus-0017-00000084801-i01.jpg

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