Sakhamuru Pavan, Nayeni Manav, Nazari Ryan, Syed Kazi, Miller Kenneth
College of Osteopathic Medicine, Kansas City University, Kansas City, USA.
Physical Medicine and Rehabilitation, Kansas City Veterans Affairs (VA) Medical Center, Kansas City, USA.
Cureus. 2025 May 26;17(5):e84853. doi: 10.7759/cureus.84853. eCollection 2025 May.
Crowned Dens Syndrome (CDS) is a rare but important consideration in the differential diagnosis of cervical spine pain in older adults. CDS is characterized by calcium pyrophosphate dihydrate (CPPD) crystal deposition around the odontoid process, often leading to symptoms that overlap with more common conditions such as rheumatoid arthritis (RA), meningitis, or cervical spondylosis. We report the case of a 74-year-old male with chronic neck pain and restricted cervical range of motion. Advanced imaging revealed characteristic calcifications surrounding the odontoid process, pannus formation, and erosive changes at the C1-C2 articulation, consistent with CDS. Clinical evaluation supported a diagnosis of CPPD-related CDS. The patient was successfully managed conservatively with nonsteroidal anti-inflammatory drugs and physical therapy, with notable symptomatic improvement over time. This case reinforces the utility of CT imaging in diagnosing CDS and differentiating it from other inflammatory or degenerative cervical conditions. Awareness of CDS and a high index of suspicion are essential for early diagnosis, appropriate treatment, and avoidance of unnecessary interventions. Conservative management remains effective in most cases; however, further studies are necessary to evaluate alternative therapies for refractory presentations.
齿状突冠综合征(CDS)是老年人颈椎疼痛鉴别诊断中一种罕见但重要的考虑因素。CDS的特征是二水焦磷酸钙(CPPD)晶体沉积在齿状突周围,常导致与类风湿性关节炎(RA)、脑膜炎或颈椎病等更常见病症重叠的症状。我们报告一例74岁男性患者,有慢性颈部疼痛和颈椎活动范围受限。高级影像学检查显示齿状突周围有特征性钙化、血管翳形成以及C1-C2关节处的侵蚀性改变,符合CDS。临床评估支持CPPD相关CDS的诊断。该患者通过非甾体类抗炎药和物理治疗成功进行了保守治疗,随着时间推移症状有明显改善。该病例强化了CT成像在诊断CDS以及将其与其他炎症性或退行性颈椎疾病相鉴别方面的作用。认识CDS并保持高度怀疑指数对于早期诊断、恰当治疗以及避免不必要的干预至关重要。在大多数情况下,保守治疗仍然有效;然而,需要进一步研究来评估针对难治性表现的替代疗法。